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The likelihood of the development to cancer is related to the degree of dysplasia. [11] Dysplasia is the earliest form of precancerous lesion which pathologists can recognize in a pap smear or in a biopsy. Dysplasia can be low grade or high grade. The risk of low-grade dysplasia transforming into high-grade dysplasia, and eventually cancer, is low.
Hereditary benign intraepithelial dyskeratosis is a rare [1] autosomal dominant disease of the conjunctiva and the oral mucosa caused by a duplication of chromosome 4q35. [2] In the mouth it appears similar to white sponge nevus, with painless, diffuse, folded and spongy white plaques. [2]
Biopsy showed mild epithelial dysplasia and candida infection. Antifungal medication may turn this type of lesion into a homogeneous leukoplakia (i.e. the red areas would disappear) Erythroleukoplakia (also termed speckled leukoplakia, erythroleukoplasia or leukoerythroplasia) is a non-homogeneous lesion of mixed white (keratotic) and red ...
White sponge naevus, Cannon's disease, Hereditary leukokeratosis of mucosa, White sponge nevus of Cannon, Familial white folded dysplasia, [1] [2] or Oral epithelial nevus [3] White sponge nevus has an autosomal dominant pattern of inheritance.
Squamous cell papilloma of the mouth or throat is generally diagnosed in people between the ages of 30 and 50, [1] and is normally found on the inside of the cheek, on the tongue, or inside of lips. Oral papillomas are usually painless, and not treated unless they interfere with eating or are causing pain. [ 1 ]
Inflammatory papillary hyperplasia (IPH) is a benign lesion of the oral mucosa which is characterized by the growth of one or more nodular lesions, measuring about 2mm or less. [4] [5] The lesion almost exclusively involves the hard palate, and in rare instances, it also has been seen on the mandible. The lesion is mostly asymptomatic and color ...
Oral submucous fibrosis (OSF) is a chronic, complex, premalignant (1% transformation risk) condition of the oral cavity, characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues (the lamina propria and deeper connective tissues). As the disease progresses, the oral mucosa becomes fibrotic to the ...
Microscopically, the tissue exhibits severe epithelial dysplasia, carcinoma-in-situ, or invasive squamous cell carcinoma in 90% of cases. There is an absence of keratin production and a reduced number of epithelial cells. Since the underlying vascular structures are less hidden by tissue, erythroplakia appears red when viewed in a clinical setting.