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  2. Engineering tolerance - Wikipedia

    en.wikipedia.org/wiki/Engineering_tolerance

    For example, if a shaft with a nominal diameter of 10 mm is to have a sliding fit within a hole, the shaft might be specified with a tolerance range from 9.964 to 10 mm (i.e., a zero fundamental deviation, but a lower deviation of 0.036 mm) and the hole might be specified with a tolerance range from 10.04 mm to 10.076 mm (0.04 mm fundamental ...

  3. Geometric dimensioning and tolerancing - Wikipedia

    en.wikipedia.org/wiki/Geometric_dimensioning_and...

    Example of true position geometric control defined by basic dimensions and datum features. Geometric dimensioning and tolerancing (GD&T) is a system for defining and communicating engineering tolerances via a symbolic language on engineering drawings and computer-generated 3D models that describes a physical object's nominal geometry and the permissible variation thereof.

  4. Tolerance analysis - Wikipedia

    en.wikipedia.org/wiki/Tolerance_analysis

    Tolerance analysis is the general term for activities related to the study of accumulated variation in mechanical parts and assemblies. Its methods may be used on other types of systems subject to accumulated variation, such as mechanical and electrical systems.

  5. Limits and fits - Wikipedia

    en.wikipedia.org/wiki/Limits_and_fits

    Clearance Fit: a fit between mating parts with positive space in-between. Parts will freely move between each other. Transition Fit: a fit between mating parts between the clearance and interference fit. Parts fit together easily enough so that force isn't required, but will still hold together on it's own.

  6. Plus–minus sign - Wikipedia

    en.wikipedia.org/wiki/Plus–minus_sign

    In medicine, it may mean "with or without" in some cases. [6] [7] In engineering, the sign indicates the tolerance, which is the range of values that are considered to be acceptable or safe, or which comply with some standard or with a contract. In chemistry, the sign is used to indicate a racemic mixture.

  7. Thymocyte - Wikipedia

    en.wikipedia.org/wiki/Thymocyte

    The double positive thymocytes undergo lineage commitment, maturing into a CD8+ T cell (recognising MHC class I) or a CD4+ T cell (recognising MHC class II). Lineage commitment occurs at the late stage of positive selection and works by downregulation of both CD4 and CD8 (reducing the signal from the T cell receptor) and then upregulation of ...

  8. Central tolerance - Wikipedia

    en.wikipedia.org/wiki/Central_tolerance

    Central tolerance is essential to proper immune cell functioning because it helps ensure that mature B cells and T cells do not recognize self-antigens as foreign microbes. [2] More specifically, central tolerance is necessary because T cell receptors (TCRs) and B cell receptors (BCRs) are made by cells through random somatic rearrangement. [1]

  9. Fault tolerance - Wikipedia

    en.wikipedia.org/wiki/Fault_tolerance

    Hardware fault tolerance sometimes requires that broken parts be taken out and replaced with new parts while the system is still operational (in computing known as hot swapping). Such a system implemented with a single backup is known as single point tolerant and represents the vast majority of fault-tolerant systems.