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The most common side effects of bicalutamide monotherapy in men are breast pain/tenderness and gynecomastia. [11] These side effects may occur in as many as 90% of men treated with bicalutamide monotherapy, [29] but gynecomastia is generally reported to occur in 70 to 80% of patients. [30]
Common side effects of bicalutamide in men include breast growth, breast tenderness, and hot flashes. [10] Other side effects in men include feminization and sexual dysfunction. [22] [23] Some side effects like breast changes and feminization are minimal when combined with castration. [24] While the medication appears to produce few side ...
Common (1–10%) General and psychiatric disorders • Asthenia • Decreased libido • Erectile dysfunction • Hot flashes: Skin and subcutaneous tissue disorders • Decreased body hair: Hepato-biliary disorders • Elevated liver enzymes [b] Uncommon (0.1–1%) Immune system disorders and hypersensitivity reactions • Angioedema • Hives
Another large study reported a rate of impotence of only 9.3% with bicalutamide relative to 6.5% for standard care (the controls), a rate of decreased libido of only 3.6% with bicalutamide relative to 1.2% for standard care, and a rate of 9.2% with bicalutamide for hot flashes relative to 5.4% for standard care. [125]
Bicalutamide is used primarily in the treatment of early and advanced prostate cancer. [1] It is approved at a dosage of 50 mg/day as a combination therapy with a gonadotropin-releasing hormone analogue (GnRH analogue) or orchiectomy (that is, surgical or medical castration) in the treatment of stage D2 metastatic prostate cancer (mPC), [2] [3] and as a monotherapy at a dosage of 150 mg/day ...
Amy Schumer once hopped on board the Ozempic trend, but the side effects were so intense she had to stop.. During a recent appearance on "The Howard Stern Show," the comedian, 43, opened up about ...
Notes: Additional cases of bicalutamide-associated adverse liver changes have been reported. These include 11 cases in a 2006 Spanish pharmacovigilance system report (including 1 case of hepatitis , 2 cases of cholestatic hepatitis , 1 case of jaundice , 4 cases of elevated liver enzymes , and 1 case of elevated bilirubin ; no deaths) [ 18 ...
On a well-known rating scale that runs from 0 to 10, the study participants started with pain of about seven, on average, and suzetrigine reduced it roughly 3.5 points. “It’s not like ...
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