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Mouse Genome Informatics (MGI) is a free, online database and bioinformatics resource hosted by The Jackson Laboratory, with funding by the National Human Genome Research Institute (NHGRI), the National Cancer Institute (NCI), and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). [1]
The laboratory also provides more than 13,000 strains of mouse models to more than 2,400 organizations in 68 countries around the world. [1] Additionally, JAX is the home of the Mouse Genome Informatics database, and an international hub for scientific courses, conferences, training and education. [7]
The NSG mouse (NOD scid gamma mouse) is a brand of immunodeficient laboratory mice, developed and marketed by Jackson Laboratory, which carries the strain NOD.Cg-Prkdc scid Il2rg tm1Wjl /SzJ. NSG branded mice are among the most immunodeficient described to date. [1] NSG branded mice lack mature T cells, B cells, and natural killer (NK) cells. [2]
MMHCdb is part of the Mouse Genome Informatics consortium (MGI) and was first released in 1998 as the Mouse Tumor Biology (MTB) database. [4] MMHCdb contains genetic and genomic information about inbred mouse strains , genetically engineered mouse models (GEMMs) and Patient Derived Xenograft (PDX) models of human cancer.
A comparison of a mouse unable to produce leptin thus resulting in obesity (left) and a normal mouse (right) The ob/ob or obese mouse is a mutant mouse that eats excessively due to mutations in the gene responsible for the production of leptin and becomes profoundly obese. It is an animal model of type II diabetes.
A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune system due to a greatly reduced number of T cells. The phenotype (main outward appearance) of the mouse is a lack of body hair, which gives it the "nude" nickname.
Yields: 4 servings. Prep Time: 25 mins. Total Time: 45 mins. Ingredients. Canola oil, for frying. 3 lb. chicken wings, drumettes and flats only. Kosher salt, to taste
The Mouse Phenome Database (MPD) is a web-accessible database of strain characterization data for the laboratory mouse, to facilitate translational research for human health and disease. MPD characterizes phenotype as well as genotype , and provides tools for online analysis.