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Doses greater than 40 000 IU (1000 μg) per day are generally required before high blood calcium occurs. [12] Normal doses, 800–2000 IU per day, are safe in pregnancy. [5] Cholecalciferol was first described in 1936. [13] It is on the World Health Organization's List of Essential Medicines. [14]
For all people over the age of 1, including women who are pregnant or lactating, they set an adequate intake of 15 μg/day (600 IU). [ 58 ] On the other hand, the EU Commission defined nutrition labelling for foodstuffs as regards recommended daily allowances (RDA) for vitamin D to 5 μg/day (200 IU) as 100%.
Based on risk assessment, a safe upper intake level of 250 μg (10,000 IU) per day in healthy adults has been suggested by non-government authors. [ 5 ] [ 6 ] Blood levels of 25-hydroxyvitamin D necessary to cause adverse effects in adults are thought to be greater than about 150 ng/mL, leading the Endocrine Society to suggest an upper limit ...
Vitamin D3, aka cholecalciferol, is important for bone health and immune function. Experts discuss benefits, sources, risks and who needs a supplement. How to get the most out of vitamin D3
Fetal alcohol syndrome usually occurs when a pregnant woman has more than four drinks per day. Milder symptoms have been found with two drinks per day during the early part of pregnancy. [53] [54] Evidence of harm from less than two drinks per day or 10 drinks per week is not clear. [53] [55]
In that study, the compliance calculation could be questionable since only random samples of the returned medications were counted. In a study by De Niet et al., [72] 60 subjects with vitamin D deficiency were randomized to receive 2000 IU vitamin D3 daily or 50 000 IU monthly. They reported a similar efficacy of the two dosing frequencies ...
Low pre-pregnancy BMI increases the risk of low birth weight infants, but the risk can be balanced by an appropriate gestational weight gain from 12.5 to 18.0 kilograms in total, or about 0.5 kilogram each week in the second and third trimesters.
Calcifediol, also known as calcidiol, 25-hydroxycholecalciferol, or 25-hydroxyvitamin D 3 (abbreviated 25(OH)D 3), [1] is a form of vitamin D produced in the liver by hydroxylation of vitamin D 3 (cholecalciferol) by the enzyme vitamin D 25-hydroxylase.