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An mRNA vaccine is a type of vaccine that uses a copy of a molecule called messenger RNA (mRNA) to produce an immune response. [1] The vaccine delivers molecules of antigen -encoding mRNA into cells , which use the designed mRNA as a blueprint to build foreign protein that would normally be produced by a pathogen (such as a virus ) or by a ...
Since the 2010s, RNA vaccines and other RNA therapeutics have been considered to be "a new class of drugs". [54] The first mRNA-based vaccines received restricted authorization and were rolled out across the world during the COVID-19 pandemic by Pfizer–BioNTech COVID-19 vaccine and Moderna, for example. [55]
Melissa J. Moore is an American biochemist who focuses on RNA. She was the Chief Scientific Officer of Moderna from 2016-2023, where her team contributed to the development of the Moderna COVID-19 vaccine .
A nucleoside-modified messenger RNA (modRNA) is a synthetic messenger RNA (mRNA) in which some nucleosides are replaced by other naturally modified nucleosides or by synthetic nucleoside analogues. [ 1 ] modRNA is used to induce the production of a desired protein in certain cells.
In January 2020, Moderna announced development of an RNA vaccine, codenamed mRNA-1273, to induce immunity to SARS-CoV-2. [ 123 ] [ 124 ] [ 125 ] Moderna received US$955 million from the Biomedical Advanced Research and Development Authority (BARDA), an office of the US Department of Health and Human Services .
Risk of heart inflammation from mRNA vaccines is being studied, creator says.
Manufacturing of mRNA vaccines can be performed rapidly in high volume, [13] including use of portable, automated printers ("RNA microfactories") for which CureVac has a joint development partnership with Tesla. [14] mRNA vaccines require stringent cold chain refrigeration throughout manufacturing, distribution and storage.
Pages in category "RNA vaccines" The following 18 pages are in this category, out of 18 total. ... Moderna COVID-19 vaccine; MRNA-1283; MRNA-4157/V940; MRNA-5671; P.
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