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The leaflets of the valve become thickened and nodular, leading to mitral valve regurgitation and volume overload of the left side of the heart. Cavalier King Charles Spaniels and Dachshunds have an inherited form of this disease. [49] Dilated cardiomyopathy (DCM) is a disease of heart muscle resulting in decreased myocardial contractility. The ...
Dogs are prone to have adverse allergic reactions to food similar to human beings. The most common symptoms of food allergies in dogs include rashes, swelling, itchy or tender skin, and gastrointestinal upsets such as uncontrollable bowel movements and soft stools. [82] Certain ingredients in dog food can elicit these allergic reactions.
Nitenpyram ( (E)-N-(6-Chloro-3-pyridylmethyl)- N-ethyl-N'-methyl-2-nitrovinylidenediamine) is an open-chain chloropyridyl neonicotinoid. Nitenpyram consists of a chloronicotinyl heterocyclic group common to all first generation neonicotinoids and a pharmacophore, the reactive group of the molecule.
Garcinia gardneriana, the bacupari, is an evergreen, dioecious species of the genus Garcinia. It is distributed throughout South America's Amazon Basin and produces ...
The use of danazol is limited by masculinizing side effects such as acne, excessive hair growth, and voice deepening. [ 2 ] [ 13 ] Danazol has a complex mechanism of action , and is characterized as a weak androgen and anabolic steroid , a weak progestogen , a weak antigonadotropin , a weak steroidogenesis inhibitor , and a functional ...
Patients who have taken pentosan polysulfate orally report a variety of side effects, primarily gastrointestinal complaints such as diarrhea, heartburn, and stomach pain. [4] Hair loss, headache, rash, and insomnia have also been reported. [4] Due to Elmiron's anticoagulant effects, some patients report bruising more easily.
Forskolin is used in biochemistry experiments to raise levels of cyclic AMP (cAMP) in studies of cell physiology. [2] [3] Forskolin activates the enzyme adenylyl cyclase and increases intracellular levels of cAMP. cAMP is an important second messenger necessary for the proper biological response of cells to hormones and other extracellular signals.
The Kombai is described as highly intelligent and extremely loyal to, and affectionate with, people they are familiar with, being particularly sweet-natured and tolerant of children with whom they allow particularly rough play, but when aroused by strangers or unfamiliar dogs they can be ferocious, making them excellent guard dogs.
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