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  2. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Factors considered before deciding on whether warfarin or a DOAC or which direct factor Xa inhibitor is used, include: the presence or absence of valvular heart disease, state of kidney function, the risk of stroke and the risk of bleeding. [8]

  3. Dabigatran - Wikipedia

    en.wikipedia.org/wiki/Dabigatran

    Dabigatran was approved for medical use in the United States in 2010. [6] It is on the World Health Organization's List of Essential Medicines. [10] In 2020, it was the 306th most commonly prescribed medication in the United States, with more than 1 million prescriptions. [11] Dabigatran is available a generic medication. [12] [13]

  4. Discovery and development of direct thrombin inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    In October 2010 the US FDA approved dabigatran etexilate for the prevention of stroke in patients with atrial fibrillation (AF). [6] [10] Many pharmaceutical companies have attempted to develop orally bioavailable DTI drugs but dabigatran etexilate is the only one to reach the market. [9]

  5. Drug overdose deaths down in Ohio, but increase in ... - AOL

    www.aol.com/drug-overdose-deaths-down-ohio...

    After Stark County reported its sixth consecutive increase in overdose deaths in 2023, local health officials say 2024 appears promising. Drug overdose deaths down in Ohio, but increase in Stark ...

  6. Overdose deaths in Ohio reached an 8-year low. Could a drug ...

    www.aol.com/news/overdose-deaths-ohio-reached-8...

    Overdose deaths in Ohio fell to an eight-year low in January. Experts disagree on why, but the answer could help save lives in the future. Overdose deaths in Ohio reached an 8-year low.

  7. Drug overdose deaths down in Ohio. Fentanyl, opioids remain ...

    www.aol.com/drug-overdose-deaths-down-ohio...

    Fewer Ohioans are dying of drug overdoses because of better access to naloxone, opioid treatment and peer support, Gov. Mike DeWine said Wednesday.

  8. Vitamin K antagonist - Wikipedia

    en.wikipedia.org/wiki/Vitamin_K_antagonist

    We undertook a post-hoc analysis of data from the ROCKET AF (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation, n = 14,624) for stroke or non-CNS embolism within 30 days after temporary interruptions of 3 days or more, early permanent ...

  9. Overdose deaths drop in Ohio, but increase in Stark ... - AOL

    www.aol.com/overdose-deaths-drop-ohio-increase...

    There was a 5% decrease in unintentional drug overdose deaths in Ohio in 2022, according to a new report. But they rose in Stark County. Overdose deaths drop in Ohio, but increase in Stark County.