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In orthopaedic medicine, a bone graft can be sourced from a patient's own bone in order to fill space and produce an osteogenic response in a bone defect. However, due to the donor-site morbidity associated with autograft, other methods such as bone allograft and bone morphogenetic proteins and synthetic graft materials are often used as alternatives.
Skin grafting, a type of graft surgery, involves the transplantation of skin without a defined circulation. The transplanted tissue is called a skin graft. [1] Surgeons may use skin grafting to treat: extensive wounding or trauma; burns; areas of extensive skin loss due to infection such as necrotizing fasciitis or purpura fulminans [2]
Autograft: graft taken from one part of the body of an individual and transplanted onto another site in the same individual, e.g., skin graft. Isograft : graft taken from one individual and placed on another individual of the same genetic constitution, e.g., grafts between identical twins .
Hence, similar tissue from another part of the body that is in excess is sourced as the autograft. [ 10 ] [ 11 ] This can be seen in procedures like autologous orthopedic transplant, which remains the "gold standard" of bone grafting methods through extracting grafts from places like the iliac crest and transplanting them to the targeted ...
Autograft, tissue transplanted from one site to another on the same patient. An autograft reduces the risk of rejection but requires a second surgery site, adding pain, risk and possible longer aftercare. Xenograft, a transplant from another species; Isograft, a transplant from a genetically identical donor, such as an identical twin.
FAMI consists of an autograft of adult stem cells in order to rebuild muscles and bones. [9] The adult stem cells are taken from an area of fatty tissue in a separate area of the body, typically from the patient's hip, knee or abdomen. The collected fat and stem cells are concentrated and refined. [10]
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Timing is important to wound healing. Critically, the timing of wound re-epithelialization can decide the outcome of the healing. [11] If the epithelization of tissue over a denuded area is slow, a scar will form over many weeks, or months; [12] [13] If the epithelization of a wounded area is fast, the healing will result in regeneration.