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Cyproheptadine, sold under the brand name Periactin among others, is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. It was patented in 1959 and came into medical use in 1961. [ 5 ]
An orexigenic, or appetite stimulant, is a drug, hormone, or compound that increases appetite and may induce hyperphagia. This can be a medication or a naturally occurring neuropeptide hormone, such as ghrelin , orexin or neuropeptide Y , [ 1 ] [ 2 ] which increases hunger and therefore enhances food consumption .
The Mayo Clinic Diet is a diet book first published in 1949 by the Mayo Clinic's committee on dietetics as the Mayo Clinic Diet Manual. [1] Prior to this, use of the term "diet" was generally connected to fad diets with no association to the clinic.
The Mayo Clinic diet, a program that adheres to this notion, was developed by medical professionals based on scientific research, so you can trust that this program is based on science, and not ...
In states where it is approved, medicinal cannabis may be prescribed for severe appetite loss, such as that caused by cancer, AIDS, or severe levels of persistent anxiety. Other drugs or supplements which may increase appetite include antihistamines (such as diphenhydramine , promethazine or cyproheptadine ).
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A subsequent 1990 study found that the elimination half-life of diphenhydramine was 5.4 hours in children, 9.2 hours in young adults, and 13.5 hours in the elderly. [7] A 1998 study found a half-life of 4.1 ± 0.3 hours in young men, 7.4 ± 3.0 hours in elderly men, 4.4 ± 0.3 hours in young women, and 4.9 ± 0.6 hours in elderly women. [82]
A lack of appetite or interest in food is a third common reason to avoid or restrict food intake. ARFID patients may perceive eating as a chore. Within this group, a low body weight or failure to thrive are common and the experienced lack of interest is long-lasting. [2] [9]