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every day (once daily) (preferred to "qd" in the UK [10]) o.d. oculus dexter: right eye o can be mistaken as an a which could read "a.d.", meaning right ear, confusion with "omni die" o.m. omni mane: every morning omn. bih. omni bihora: every 2 hours omn. hor. omni hora: every hour o.n. omni nocte: every night OPD once per day o.s.
Half-life elimination is 6–7 days for people with normal lab results; 9–10 days for people with hypothyroidism; 3–4 days for people with hyperthyroidism. [18] Thyroid hormones are primarily eliminated by the kidneys (about 80%), with urinary excretion decreasing with age. [18] The remaining 20% of T 4 is eliminated in the stool. [18]
The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable expectancy of ...
Dosage typically includes information on the number of doses, intervals between administrations, and the overall treatment period. [3] For example, a dosage might be described as "200 mg twice daily for two weeks," where 200 mg represents the individual dose, twice daily indicates the frequency, and two weeks specifies the duration of treatment.
The therapeutic index (TI; also referred to as therapeutic ratio) is a quantitative measurement of the relative safety of a drug with regard to risk of overdose.It is a comparison of the amount of a therapeutic agent that causes toxicity to the amount that causes the therapeutic effect. [1]
The dose schedule given every two weeks is as follows: [5] Day 1–2: Oxaliplatin 100 mg/m 2 IV infusion, given as a 120 minutes IV infusion in 500 mL D5W, concurrent with leucovorin 400 mg/m 2 (or levoleucovorin 200 mg/m 2) IV infusion, followed by 5-FU 400 mg/m 2 IV bolus, followed by 46-hour 5-FU infusion (2400 mg/m 2 for first two cycles, and may be increased to 3000 mg/m 2 if tolerated by ...
Threshold dose is the minimum dose of drug that triggers minimal detectable biological effect in an animal. [1] At extremely low doses, biological responses are absent for some of the drugs. The increase in dose above threshold dose induces an increase in the percentage of biological responses. [ 2 ]
The notice period depends on the employee’s length of service within the company as follows: 7 days during the trial period; 1 month if employed below 1 year; 2 months if employed below 10 years; 3 months if employed more than 10 years; The default trial period is the first month of employment, but may be extended up to three months.