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Injury is physiological damage to the living tissue of any organism, whether in humans, in other animals, or in plants. Injuries can be caused in many ways, including mechanically with penetration by sharp objects such as teeth or with blunt objects , by heat or cold, or by venoms and biotoxins .
Major trauma is a severe traumatic injury that has the potential to cause disability or death. Serious traumatic injury most often occurs as a result of traffic collisions. [11] Traumatic injury is the leading cause of death in people under the age of 45. [12] Blunt trauma injuries are caused by the forceful impact of an external object.
Abdominal CT showing left renal artery injury. Blunt abdominal trauma (BAT) represents 75% of all blunt trauma and is the most common example of this injury. [3] Seventy-five percent of BAT occurs in motor vehicle crashes, [4] in which rapid deceleration may propel the driver into the steering wheel, dashboard, or seatbelt, [5] causing contusions in less serious cases, or rupture of internal ...
Reperfusion injury, sometimes called ischemia-reperfusion injury (IRI) or reoxygenation injury, is the tissue damage caused when blood supply returns to tissue (re-+ perfusion) after a period of ischemia or lack of oxygen (anoxia or hypoxia).
Hyper-flexion is a common mechanism of injury in the cervical spine associated with an anterior compression vector and a posterior distraction vector. [18] These injuries are associated with diving injuries, falls and car accidents. [18]
External Cause of Injury Codes (E codes) are ICD-9-CM codes or ICD-10 codes that are used to define the mechanism of death or injury, along with the place of occurrence of the event. E codes are assigned on death certificates based on the manner of death. ICD-10 codes in the range V01–X59 refer to unintentional injuries.
Inflammation after injury occurs to protect against further damage and starts the healing process. Prolonged inflammation may cause multiple organ dysfunction syndrome or systemic inflammatory response syndrome. [21] Immediately after injury, the body increases production of glucose through gluconeogenesis and its consumption of fat via lipolysis.
Closed head injury (coup contrecoup) can damage more than the impact sites on the brain, as axon bundles may be torn or twisted, blood vessels may rupture, and elevated intracranial pressure can distort the walls of the ventricles. [7] [10] [11] Diffuse axonal injury is a key pathology in concussive brain injury. [5] The visual system may be ...
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