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Crush injury is compression of the arms, legs, or other parts of the body that causes muscle swelling and/or neurological disturbances in the affected areas of the body, while crush syndrome is a localized crush injury with systemic manifestations. [1]
It can also affect the thigh, buttock, hand, abdomen, and foot. [19] [14] The most common cause of acute compartment syndrome is a fractured bone, usually the tibia. [14] [27] Leg compartment syndrome occurs in 1% to 10% of tibial fractures. [6] It is strongly linked to tibial diaphysis fractures and other tibial injuries. [28]
Phocomelia is a congenital condition that involves malformations of human arms and legs which result in a flipper-like appendage. [1] [2] A prominent cause of phocomelia is the mother being prescribed the use of the drug thalidomide during pregnancy; however, the causes of most cases are to be determined. [2]
This mouse strain recapitulates many of the features of the human disease and promises to provide insights into the pathogenesis of the disease. Reducing the level of normal fibrillin 1 causes a Marfan-related disease in mice. [34] Transforming growth factor beta plays an important role in MFS. Fibrillin-1 directly binds a latent form of TGF-β ...
Myotonia congenita is a congenital neuromuscular channelopathy that affects skeletal muscles (muscles used for movement). It is a genetic disorder.The hallmark of the disease is the failure of initiated contraction to terminate, often referred to as delayed relaxation of the muscles and rigidity. [1]
Hip and leg pain. Numbness, weakness or pain in your hands or feet. Painful, swollen eyes or eyelids, and/or vision loss. Stage 3 symptoms can include: Any combination of symptoms from previous stages
Tetrapod legs evolved in the Devonian or Carboniferous geological period from the pectoral fins and pelvic fins of their crossopterygian fish ancestors. Fish fins develop along a "fin line", which runs from the back of the head along the midline of the back, round the end of the tail, and forwards along the underside of the tail, and at the cloaca splits into left and right fin lines which run ...
These processes cause the typical symptoms of fainting: pale skin, rapid breathing, nausea, and weakness of the limbs, particularly of the legs. [3] If the ischemia is intense or prolonged, limb weakness progresses to collapse. [3] The weakness of the legs causes most people to sit or lie down if there is time to do so.