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  2. Citrullination - Wikipedia

    en.wikipedia.org/wiki/Citrullination

    The chemical conversion of arginine to citrulline, known as citrullination or deimination. Citrullination or deimination is the conversion of the amino acid arginine in a protein into the amino acid citrulline. Citrulline is not one of the 20 standard amino acids encoded by DNA in the genetic code.

  3. Arginine - Wikipedia

    en.wikipedia.org/wiki/Arginine

    Arginine is made by the body as follows. The epithelial cells of the small intestine produce citrulline, primarily from glutamine and glutamate, which is secreted into the bloodstream which carries it to the proximal tubule cells of the kidney, which extract the citrulline and convert it to arginine, which is returned to the blood. This means ...

  4. How Long Does It Take for L-Citrulline to Work for ED? - AOL

    www.aol.com/long-does-l-citrulline-ed-105700234.html

    During this process, an amino acid produced by the body, L-citrulline, is converted to L-arginine, another type of amino acid. This is where L-citrulline supplementation comes in: Some people take ...

  5. Histone-modifying enzymes - Wikipedia

    en.wikipedia.org/wiki/Histone-modifying_enzymes

    The amino acid arginine (left) is converted to citrulline (right) via the process of citrullination. Citrullination, or deimination, is the process by which the amino acid arginine (R) is converted into citrulline. Protein arginine deiminases (PADs) replace the ketimine group of arginine with a ketone group to form the citrulline.

  6. Citrulline - Wikipedia

    en.wikipedia.org/wiki/Citrulline

    The organic compound citrulline is an α-amino acid. [2] Its name is derived from citrullus, the Latin word for watermelon.Although named and described by gastroenterologists since the late 19th century, it was first isolated from watermelon in 1914 by Japanese researchers Yatarō Koga (古賀彌太郎) and Ryō Ōtake (大嶽了) [3] [4] and further codified by Mitsunori Wada of Tokyo ...

  7. Do Nitric Oxide Supplements Really Help With ED? - AOL

    www.aol.com/nitric-oxide-supplements-really-help...

    Notably, a study looking at L-arginine and L-citrulline levels in men found that men with severe ED with an arteriogenic etiology had lower levels of these two amino acids, indicating a possible ...

  8. Argininosuccinate synthase - Wikipedia

    en.wikipedia.org/wiki/Argininosuccinate_synthase

    The enzyme endothelial nitric oxide synthase produces nitric oxide from arginine in endothelial cells. [9] Argininosuccinate synthetase and argininosuccinate lyase recycle citrulline, a byproduct of nitric oxide production, into arginine. Since nitric oxide is an important signaling molecule, this role of ASS is important to vascular physiology.

  9. Anti–citrullinated protein antibody - Wikipedia

    en.wikipedia.org/wiki/Anti–citrullinated...

    During inflammation, arginine amino acid residues can be enzymatically converted into citrulline residues in proteins such as vimentin, by a process called citrullination. If their shapes are significantly altered, the proteins may be seen as antigens by the immune system, thereby generating an immune response. [2]

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