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[4] [5] [6] According to Pender (1972), "the state has been designated as dissociative anesthesia since the patient truly seems disassociated from his environment." [ 7 ] Both Pender (1970) and Johnstone et al. (1959) reported that patients under anaesthesia due to either ketamine or phencyclidine were prone to purposeless movements and had ...
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Methoxetamine (MXE) is a dissociative hallucinogen that has been sold as a designer drug. [5] [6] It differs from many dissociatives such as ketamine and phencyclidine (PCP) that were developed as pharmaceutical drugs for use as general anesthetics in that it was designed specifically to increase the antidepressant effects of ketamine.
Deoxymethoxetamine (3'-methyl-2-oxo-PCE, DMXE, 3D-MXE) is a recreational designer drug from the arylcyclohexylamine family, with dissociative effects. It is an analogue of methoxetamine where the 3-methoxy group has been replaced by methyl. It has been sold online since around October 2020, and was first definitively identified by a forensic ...
Ketamine is a drug used for anesthesia, and is also used as a recreational drug, both in powder and liquid form, for its hallucinogenic and dissociative effects. [ 38 ] Some national laws prohibit the use of different recreational drugs; medicinal drugs that have the potential for recreational use are often heavily regulated.
Dissociative disorders are characterized by distinct brain differences in the activation of various brain regions including the inferior parietal lobe, prefrontal cortex, and limbic system. [16] Those with dissociative disorders have higher activity levels in the prefrontal lobe and a more inhibited limbic system on average than healthy ...
Diphenidine (1,2-DEP, DPD, DND) is a dissociative anesthetic that has been sold as a designer drug. [2] [3] [4] The synthesis of diphenidine was first reported in 1924, and employed a Bruylants reaction analogous to the one that would later be used to discover phencyclidine in 1956. [2]
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