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Early infection tends to be associated with mild or no symptoms, while the later pulmonary phase, which can be life-threatening in adults, is usually mild or absent. [32] [33] While cases of children with severe symptoms are exceptional, they can occasionally require intensive care. [34] [35] [36] Fatalities have been rare. [33] [37]
Clinical trials show that anti-interleukin-6 and anti-interleukin-1 drugs are effective in managing systemic symptoms. Studies show that 40% of children with SJIA have a monocyclic disease history, recovering after varying periods. A small percentage experience a polycyclic course, with over half having a prolonged disease course.
A systemic disease is one that affects a number of organs and tissues, or affects the body as a whole. [1] It differs from a localized disease , which is a disease affecting only part of the body (e.g., a mouth ulcer ).
20 per 100,000 children under age 5 [31] Giant cell arteritis: Large and medium arteries, can affect coronary arteries None specific Confirmed 200 per 100,000 (over age 50) [32] [33] Takayasu's arteritis: Large arteries, including the aorta: None specific Confirmed Rare, more common in East Asia [33] [34] Behçet's disease
Kawasaki disease (KD) is a type of systemic vasculitis of medium-sized vessels with an acute onset that primarily affects young children. Fever, conjunctivitis, infection of the skin and mucous membranes, and cervical lymphadenopathy are the main symptoms. [11]
HSP is often preceded by an infection, such as a throat infection. HSP is a systemic vasculitis (inflammation of blood vessels) and is characterized by deposition of immune complexes containing the antibody immunoglobulin A (IgA); the exact cause for this phenomenon is unknown. In children, it usually resolves within several weeks and requires ...
In immunology, systemic inflammatory response syndrome (SIRS) is an inflammatory state affecting the whole body. [1] It is the body's response to an infectious or noninfectious insult . Although the definition of SIRS refers to it as an "inflammatory" response, it actually has pro- and anti-inflammatory components.
Calicivirus infection (Norovirus and Sapovirus) No Campylobacter species Campylobacteriosis: Stool culture Erythromycin can be used in children, and tetracycline in adults. No usually Candida albicans and other Candida species Candidiasis (Moniliasis; Thrush) oral candidiasis, the person's mouth for white patches and irritation.