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Alcohol breaks down in the body into a substance called acetaldehyde, which can damage your cells and stop them from repairing themselves. That creates the conditions for cancer to grow.
Intoxication does have real physiological effects, such as altering a drinker's perception of space and time, reducing psychomotor skills, and disrupting equilibrium. [74] But some effects and the degree of the effects that are attributed to alcohol can be due to the expectations rather than the substance itself, [75] similar to the placebo ...
The initial buzz and immediate effects of alcohol may be familiar. Here’s how the long-term consequences of excessive drinking can gradually take a toll on your health. 1.
You may have heard warnings about the way alcohol can damage the liver, but it can also affect organs throughout your entire body. And it starts as soon as you take a sip.
The reinforcing effects of alcohol consumption are mediated by acetaldehyde generated by catalase and other oxidizing enzymes such as cytochrome P-4502E1 in the brain. [60] Although acetaldehyde has been associated with some of the adverse and toxic effects of ethanol, it appears to play a central role in the activation of the mesolimbic ...
Alcohol affects the nutritional state of chronic drinkers. It can decrease food consumption and lead to malabsorption. It can also create imbalances in skeletal muscle mass and cause muscle wasting. Chronic consumption of alcohol can also increase the breakdown of important proteins in the body which can affect gene expression. [157]
The excess amount of blood aldehyde produce facial flushing, nausea, rapid heartbeat, and other adverse effects. [26] [27] Presence of these alleles causes rapid conversion of alcohol to acetaldehyde which can be toxic in large amount. So, the East Asians and Africans feel the adverse effects of alcohol early and stop drinking.
If you have an inherited intolerance to alcohol, a mutated gene could be the culprit. An at-home DNA test could detect whether you have the mutation, but doctors say there could be some drawbacks.