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Poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species Enterovirus C, in the family of Picornaviridae. [1] There are three poliovirus serotypes, numbered 1, 2, and 3. Poliovirus is composed of an RNA genome and a protein capsid.
Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.
Polio is “shorthand for poliomyelitis, a disease of the central nervous system caused by infection with poliovirus,” Dr. Richard Lloyd, professor of molecular virology and microbiology at ...
Post-polio syndrome (PPS, poliomyelitis sequelae) is a group of latent symptoms of poliomyelitis (polio), occurring in more than 80% of polio infections. The symptoms are caused by the damaging effects of the viral infection on the nervous system and typically occur 15 to 30 years after an initial acute paralytic attack.
A child receives oral polio vaccine during a 2002 campaign to immunize children in India. Poliovirus. Polio eradication, the goal of permanent global cessation of circulation of the poliovirus and hence elimination of the poliomyelitis (polio) it causes, is the aim of a multinational public health effort begun in 1988, led by the World Health Organization (WHO), the United Nations Children's ...
Polio: An American Story by David M. Oshinsky, professor of history at the University of Texas at Austin, documents the polio epidemic in the United States during the 1940s and 1950s and the race to develop a vaccine, which led to 2 different types of polio vaccine: inactivated poliovirus vaccine, developed by a team led by Jonas Salk, and oral poliovirus vaccine, developed by a team led by ...
At the height of the epidemic, which was from June 1 to November 1, the death rate from polio in the greater New York City area was 26.9%. Out of all the deaths from polio during this span, 83% of them were of children under 5 years of age, while only 2.5% of the deaths were of people over the age of 16. [6]
Widespread immunization has substantially reduced the morbidity and mortality rates from diseases such as tuberculosis, poliomyelitis, measles, diphtheria, tetanus, pertussis, hepatitis B, yellow fever, meningitis A and many others. Recent innovations have expanded the impact of vaccines in addressing not only childhood diseases but also adult ...