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Dr. Thomas’ Eclectric Oil was a widely used pain relief remedy which was sold in Canada and the United States as a patent medicine from the 1850s into the early twentieth century. [ 1 ] [ 2 ] Like many patent medicines, it was advertised as a unique cure-all , but mostly contained common ingredients such as turpentine and camphor oil .
Joseph Thomas Clover (born 28 February 1825; baptised 7 May 1825 – 27 September 1882) [2] was an English doctor and innovator of anaesthesia.He invented a variety of pieces of apparatus to deliver anaesthetics, including ether and chloroform, safely and controllably.
Samuel Guthrie was born in Brimfield, in Hampden's county, Massachusetts, in 1782 [1] "Dr. Guthrie was of dark complexion, medium stature, slender build, slightly stooping figure, and thoughtful mien; his head was well-formed and of full medium size, features slightly oval, nose prominent and a little irregular in shape."
In Canada, a wide range of basic laboratory reagents such as nitric acid and hydrogen peroxide are restricted as "explosives precursors". [37] Two of the main legal texts in Canada restricting the sale of certain chemicals are the Explosives Act, [ 38 ] and the Explosives Regulations, 2013 (SOR/2013-211). [ 39 ]
The reactivity of chloroformates and acyl chlorides are similar. Representative reactions are: Reaction with amines to form carbamates: [2]; ROC(O)Cl + H 2 NR' → ROC(O)-N(H)R' + HCl
supplying chloroform for the first human use to James Young Simpson William Flockhart, L.R.C.S.E. (1808 – 1871) was a Scottish chemist, a pharmacist who provided chloroform to Doctor (later Sir) James Young Simpson for his anaesthesia experiment at 52 Queen Street , Edinburgh on 4 November 1847. [ 1 ]
Thus, the detriments of consuming herbal tonics are largely unknown to the greater population; further, there is an assumption herbal remedies and medicines are safe. [ 8 ] There are accounts of toxicity as a result of consuming herbal tonics causing severe abdominal pain, malaise and in some cases, even liver failure.
Chloramine also has a much lower, but still active, tendency than free chlorine to convert organic materials into chlorocarbons such as chloroform and carbon tetrachloride. Such compounds have been identified as carcinogens and in 1979 the United States Environmental Protection Agency (EPA) began regulating their levels in US drinking water .