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Physical characteristics of a Klinefelter syndrome can be tall stature, low body hair, and occasionally an enlargement of the breast. Usually, a small testicle volume of 1–5 ml per testicle (standard values: 12–30 ml) occurs. [32]
In Edinburgh, Scotland, eight 47,XYY boys born 1967–1972 and identified in a newborn screening programme had an average height of 188.1 cm (6 ft 2 in) at age 18—their fathers' average height was 174.1 cm (5 ft 8 + 1 ⁄ 2 in), their mothers' average height was 162.8 cm (5 ft 4 + 1 ⁄ 8 in).
Like Klinefelter syndrome, the presence of additional X chromosomes affects the male reproductive system, can cause physical abnormalities, and can affect cognitive development. When comparing 47,XXY and 48,XXXY, there is a greater risk for congenital malformations and more medical problems in those with 48,XXXY. [2]
Sex chromosome aneuploidies [note 1] are generally associated with tall stature, particularly polysomies of the Y chromosome, but data on tetrasomy and pentasomy disorders [note 2] is less clear and some seem associated with short stature; [6] [7] adult XXXYY men in the medical literature have ranged in height from 170 centimetres (5 ft 7 in ...
48,XXYY syndrome is a condition related to the X and Y chromosomes (the sex chromosomes). People normally have 46 chromosomes in each cell.Two of the 46 chromosomes, known as X and Y, are called sex chromosomes because they help determine whether a person will develop male or female sex characteristics.
XX male syndrome, also known as de la Chapelle syndrome, is a rare intersex condition in which an individual with a 46,XX karyotype develops a male phenotype. [2] Synonyms for XX male syndrome include 46,XX testicular difference of sex development (or 46,XX DSD) [3] [4] [5] [6]
The body mass index (BMI) considers the height-weight relationship as a health indicator, while the body roundness index (BRI) measures abdominal body fat and height. BMI has often been criticized ...
Sexual differentiation includes development of different genitalia and the internal genital tracts and body hair plays a role in sex identification. [ 2 ] The development of sexual differences begins with the XY sex-determination system that is present in humans, and complex mechanisms are responsible for the development of the phenotypic ...