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Corneal smears or impression cytology specimens can be analyzed by culture, antigen detection, or fluorescent antibody testing. Tzanck smear, i.e.Papanicolaou staining of corneal smears [ further explanation needed ] , show multinucleated giant cells and intranuclear inclusion bodies, however, the test is low in sensitivity and specificity.
Corneal hydrops is an uncommon complication seen in people with advanced keratoconus or other corneal ectatic disorders, [1] and is characterized by stromal edema due to leakage of aqueous humor through a tear in Descemet's membrane. [2]
Edema may also be found in the cornea of the eye with glaucoma, severe conjunctivitis, keratitis, or after surgery. Affected people may perceive coloured haloes around bright lights. Edema surrounding the eyes is called periorbital edema (puffy eyes) . The periorbital tissues are most noticeably swollen immediately after waking, perhaps as a ...
Bullous keratopathy, also known as pseudophakic bullous keratopathy (PBK), is a pathological condition in which small vesicles, or bullae, are formed in the cornea due to endothelial dysfunction. In a healthy cornea, endothelial cells keeps the tissue from excess fluid absorption, pumping it back into the aqueous humor.
Posterior corneal dystrophies – Fuchs corneal dystrophy presents during the fifth or sixth decade of life. The characteristic clinical findings are excrescences on a thickened Descemet membrane (cornea guttae), generalized corneal edema and decreased visual acuity. In advanced cases, abnormalities are found in all the layers of the cornea.
The Chandler variant of ICE is characterized by pathology on the inner surface of the cornea leading to abnormal endothelial pump function. [2] [5] Other features include possible mild iris changes, corneal edema, and normal to slight elevations in intraocular pressure. [1] [5] Cogan-Reese variant is characterized by multiple pigmented iris ...
The typical infant who has congenital glaucoma usually is initially referred to an ophthalmologist because of apparent corneal edema. The commonly described triad of epiphora (excessive tearing), blepharospasm and photophobia may be missed until the corneal edema becomes apparent.
Macular edema occurs when fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken and swell . The swelling may distort a person's central vision , because the macula holds tightly packed cones that provide sharp, clear, central vision to enable a person to see detail ...