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The blood brain barrier restricts diffusion to small hydrophobic molecules, making drug diffusion difficult to achieve. Blood flow is directly influenced by the thermodynamics of the body. Changes in temperature affect the viscosity and surface tension of the blood, altering the minimum blood flow rate.
The microcirculation has three major components: pre-capillary, capillary, and post-capillary. In the pre-capillary sector, arterioles, and precapillary sphincters participate. Their function is to regulate blood flow before it enters the capillaries and venules by the contraction and relaxation of the smooth muscle found on their walls.
Biological fluid Dynamics (or Biofluid Dynamics) involves the study of the motion of biological fluids (e.g. blood flow in arteries, animal flight, fish swimming, etc.). It can be either circulatory system or respiratory systems. Understanding the circulatory system is one of the major areas of research.
Digestion is the breakdown of large insoluble food compounds into small water-soluble components so that they can be absorbed into the blood plasma. In certain organisms, these smaller substances are absorbed through the small intestine into the blood stream.
Micrograph of paper autofluorescing under ultraviolet illumination. The individual fibres in this sample are around 10 μm in diameter.. Autofluorescence is the natural fluorescence of biological structures such as mitochondria and lysosomes, in contrast to fluorescence originating from artificially added fluorescent markers (fluorophores).
Therefore, bioavailability for dietary supplements can be defined as the proportion of the administered substance capable of being absorbed and available for use or storage. [11] In both pharmacology and nutrition sciences, bioavailability is measured by calculating the area under curve (AUC) of the drug concentration time profile.
The ECF can also be seen as having two components – plasma and lymph as a delivery system, and interstitial fluid for water and solute exchange with the cells. [ 6 ] The extracellular fluid, in particular the interstitial fluid, constitutes the body's internal environment that bathes all of the cells in the body.
In the case of skin cells, extra blood flow in them is used for thermoregulation of a body. In addition to delivering oxygen , blood flow helps to dissipate heat in a body by redirecting warm blood closer to its surface where it can help to cool a body through sweating and thermal dissipation .