Search results
Results from the WOW.Com Content Network
The dose–response relationship, or exposure–response relationship, describes the magnitude of the response of an organism, as a function of exposure (or doses) to a stimulus or stressor (usually a chemical) after a certain exposure time. [1] Dose–response relationships can be described by dose–response curves. This is explained further ...
The linear no-threshold model (LNT) is a dose-response model used in radiation protection to estimate stochastic health effects such as radiation-induced cancer, genetic mutations and teratogenic effects on the human body due to exposure to ionizing radiation. The model assumes a linear relationship between dose and health effects, even for ...
The study shows a linear dose response for all solid tumors. [6] This means the relationship between dose and human body response is a straight line. [6] To see an example, look at the graph titled "Linear graph." Linear dose response also means that the rate of change of human body response is the same at any dose. [7]
Radiation dosimetry in the fields of health physics and radiation protection is the measurement, calculation and assessment of the ionizing radiation dose absorbed by an object, usually the human body. This applies both internally, due to ingested or inhaled radioactive substances, or externally due to irradiation by sources of radiation.
In toxicology it is specifically the highest tested dose or concentration of a substance (i.e. a drug or chemical) or agent (e.g. radiation), at which no such adverse effect is found in exposed test organisms where higher doses or concentrations resulted in an adverse effect. [3] [4] [5]
Threshold dose is a dose of drug barely adequate to produce a biological effect in an animal. In dose-response assessment, the term ‘threshold dose’ is refined into several terminologies, such as NOEL, NOAEL, and LOAEL. They define the limits of doses resulting in biological responses or toxic effects. [3]
The relative biological effectiveness for radiation of type R on a tissue is defined as the ratio = where D X is a reference absorbed dose of radiation of a standard type X, and D R is the absorbed dose of radiation of type R that causes the same amount of
One such application is Dose–response relationship, or the examination of the minimum required dose of radiation it takes to receive certain therapeutic outcomes including cell inactivation. There are clinical applications that highlight things such as Focused ultrasound and Gamma knife surgeries and procedures to treat brain tumors, abnormal ...