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Benzodiazepine withdrawal syndrome (BZD withdrawal) is the cluster of signs and symptoms that may emerge when a person who has been taking benzodiazepines as prescribed develops a physical dependence on them and then reduces the dose or stops taking them without a safe taper schedule.
The signs and symptoms of benzodiazepine dependence include feeling unable to cope without the drug, unsuccessful attempts to cut down or stop benzodiazepine use, tolerance to the effects of benzodiazepines, and withdrawal symptoms when not taking the drug.
A markedly increased risk of cancer was found in users of sleeping pills, mainly benzodiazepines. [64] Fifteen epidemiologic studies have suggested that benzodiazepine or nonbenzodiazepine hypnotic drug use is associated with increased mortality, mainly due to increased cancer death.
Chlordiazepoxide is generally considered an inappropriate benzodiazepine for the elderly due to its long elimination half-life and the risks of accumulation. [10] Benzodiazepines require special precaution if used in the elderly, pregnancy, children, alcohol- or drug-dependent individuals and individuals with comorbid psychiatric disorders .
The exact cause is a bit of a mystery. But brain zaps are likely due to a “neurotransmitter readjustment” in your brain when you stop an antidepressant, Dr. Gold says.
Clonazepam, a benzodiazepine is used to treat many forms of parasomnia. [77] Rapid eye movement behavior disorder responds well to low doses of clonazepam. [78] [79] Restless legs syndrome can be treated using clonazepam as a third line treatment option as the use of clonazepam is still investigational. [80] [81]
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In letters home from an abstinence-based facility in Prestonsburg, Kentucky, Kayla Haubner gushed about how she was taking to the program, but worried it wouldn’t be enough. “I’m so ready to stay sober,” she wrote in early 2013. “Believe me, I know how hard it’s gonna be when I leave here + go back into the real world. I’m safe ...