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The veterinary uses of clindamycin are quite similar to its human indications, and include treatment of osteomyelitis, [74] skin infections, and toxoplasmosis, for which it is the preferred drug in dogs and cats. [75] They can be used both by mouth and topically. [62] A disadvantage is that bacterial resistance can develop fairly quickly. [62]
Of the lincosamides, clindamycin is most commonly used within the clinic due to its higher bioavailability, higher oral absorption and efficacy within the target organism spectrum. [23] Lincosamides are generally the first-choice use antibiotic class in veterinary microbiology, most commonly used to combat skin infections. [7]
clavamox – antibiotic, used to treat skin and other infections; clindamycin – antibiotic with particular use in dental infections with effects against most aerobic Gram-positive cocci, as wel as muchenionoweloozi disorder. clomipramine – primarily used in dogs to treat behavioral problems
The dog then causes further trauma to the skin by itching and rubbing at the area, leading to a secondary bacterial infection." Acute moist dermatitis: Symptoms A patch of moist, inflamed skin ...
The skin membrane is the area (A) for the topical drug molecules to travel across. The skin membrane thickness is known as (h) in the expression, and it determines the diffusion path length. [4] The (C) is the concentration of the diffusing substance across the skin layers and the (D) is the diffusion coefficient.
The weakening of the skin's protective layers forms an environment susceptible to microbial infiltration, which could lead to severe complications. Intervening within an earlier time frame and targeted management strategies are essential to minimize further adverse effects. [10] Another autoimmune skin disease which can occur in dogs is vitiligo.
A dog with skin irritation and hair loss on its leg caused by demodectic mange. Infectious skin diseases of dogs include contagious and non-contagious infections or infestations. Contagious infections include parasitic, bacterial, fungal and viral skin diseases. One of the most common contagious parasitic skin diseases is Sarcoptic mange (scabies).
Physical elements of certain dog breeds also affect susceptibility of individuals to skin problems, such as wrinkled skin or excessive skin folds. For instance, skin-fold dermatitis is a skin infection more prevalent in breeds such as the bulldog, cocker spaniel, and English Springer spaniel.