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Mouse Genome Informatics (MGI) is a free, online database and bioinformatics resource hosted by The Jackson Laboratory, with funding by the National Human Genome Research Institute (NHGRI), the National Cancer Institute (NCI), and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). [1]
Database Institute / Organization Alteration Types Primary Source [t 1] Processed Data [t 2] Organisms Cell lines [t 3] Public Data [t 4] Restricted Data [t 5]; The BioExpress® Oncology Suite from Ocimum Bio Solutions contains gene expression data from primary, metastatic, and benign tumor samples, and normal samples, including matched adjacent controls.
The Expression Atlas allows searches by gene, splice variant, protein attribute, disease, treatment or organism part (cell types/tissues). Individual genes or gene sets can be searched for. All datasets in Expression Atlas have its metadata manually curated and its data analysed through standardised analysis pipelines.
Today the Biohub is launching Tabula Muris, an open-source database that details the biology of the average healthy mouse cell-by-cell, providing a potential gold mine for medical researchers.
EMAGE (e-Mouse Atlas of Gene Expression [note 1]) is an online biological database of gene expression data in the developing mouse (Mus musculus) embryo. [1] [2] [3] The data held in EMAGE is spatially annotated to a framework of 3D mouse embryo models produced by EMAP (e-Mouse Atlas Project).
GeneNetwork is a combined database and open-source bioinformatics data analysis software resource for systems genetics. [1] This resource is used to study gene regulatory networks that link DNA sequence differences to corresponding differences in gene and protein expression and to variation in traits such as health and disease risk.
Reactome is a free online database of biological pathways. [ 1 ] [ 2 ] [ 3 ] It is manually curated and authored by PhD-level biologists, in collaboration with Reactome editorial staff. The content is cross-referenced to many bioinformatics databases.
ANNOVAR is a command-line tool written in the Perl programming language and can be run on any operating system that has a Perl interpreter installed. [1] If used for non-commercial purposes, it is available free as an open-source package that is downloadable through the ANNOVAR website.