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  2. Cell culture - Wikipedia

    en.wikipedia.org/wiki/Cell_culture

    Cell culture is a fundamental component of tissue culture and tissue engineering, as it establishes the basics of growing and maintaining cells in vitro. The major application of human cell culture is in stem cell industry, where mesenchymal stem cells can be cultured and cryopreserved for future use. Tissue engineering potentially offers ...

  3. Microcarrier - Wikipedia

    en.wikipedia.org/wiki/Microcarrier

    Microcarrier cell culture, however, was the breakthrough required for cell culture to reach industrial and clinical significance. [2] Studies have shown that microcarrier suspensions, compared to multi-layer vessel culture, improve cell yield by 80-fold at only ten percent of Good Manufacturing Practice space, and only sixty percent of the ...

  4. Cell-based models - Wikipedia

    en.wikipedia.org/wiki/Cell-based_models

    Cell-based models are mathematical models that represent biological cells as discrete entities. Within the field of computational biology they are often simply called agent-based models [1] of which they are a specific application and they are used for simulating the biomechanics of multicellular structures such as tissues. to study the influence of these behaviors on how tissues are organised ...

  5. Microfluidic cell culture - Wikipedia

    en.wikipedia.org/wiki/Microfluidic_cell_culture

    Mixed co-culture is the simplest co-culture method, where two types of cells are in direct contact within a single culture compartment at the desired cell ratio. [47] Cells can communicate by paracrine and juxtacrine signaling, but separated treatments and downstream analysis of a single cell type are not readily feasible due to the completely ...

  6. Cellular model - Wikipedia

    en.wikipedia.org/wiki/Cellular_model

    A cellular model is a mathematical model of aspects of a biological cell, for the purposes of in silico research. Developing such models has been a task of systems biology and mathematical biology .

  7. Primary cell culture - Wikipedia

    en.wikipedia.org/wiki/Primary_cell_culture

    Primary cell culture is the ex vivo culture of cells freshly obtained from a multicellular organism, as opposed to the culture of immortalized cell lines.In general, primary cell cultures are considered more representative of in vivo tissues than cell lines, and this is recognized legally in some countries such as the UK (Human Tissue Act 2004). [1]

  8. Adherent culture - Wikipedia

    en.wikipedia.org/wiki/Adherent_Culture

    Adherent cell cultures are a type of cell culture that requires cells to be attached to a surface in order for growth to occur. [1] Most vertebrate-derived cells (with the exception of hematopoietic cells) are anchorage dependent and require a two-dimensional monolayer to facilitate cell adhesion, spreading and replication. [2]

  9. U937 (cell line) - Wikipedia

    en.wikipedia.org/wiki/U937_(cell_line)

    U-937 cells are a pro-monocytic model cell line used in biomedical research. [1] They were isolated from the histiocytic lymphoma of a 37-year-old male patient in 1974. [2] Due to the relative uniformity of expanded cultures and lower maintenance requirements these cells have been since used as an important tool for studying phagocyte differentiation and different kinds of cell-to-cell ...