Search results
Results from the WOW.Com Content Network
A thrombin generation assay (TGA) or thrombin generation test (TGT) is a global coagulation assay (GCA) and type of coagulation test which can be used to assess coagulation and thrombotic risk. [ 1 ] [ 2 ] [ 3 ] It is based on the potential of a plasma to generate thrombin over time, following activation of coagulation via addition of ...
Levo-Transposition of the great arteries (also known as Levo-TGA, congenitally corrected TGA, double discordance, or ventricular inversion) is a rare, acyanotic heart defect in which the primary arteries are transposed, with the aorta anterior and to the left of the pulmonary artery, and the morphological left and right ventricles with their ...
Simple l-TGA does not produce any visually identifiable features at birth. However, systemic blood pressure then becomes much higher than pulmonary blood pressure. The morphological right ventricle, evolved to handle a low blood pressure, will over a period of years hypertrophy and may fail, because of the high pressure it is forced to work against.
cyanotic d-TGA + VSD neonate (unpalliated and pre-operative) Due to the low oxygen saturation of the blood, cyanosis will appear in peripheral areas: around the mouth and lips, fingertips, and toes; these areas are furthest from the heart, and since the circulated blood is not fully oxygenated to begin with, very little oxygen reaches the peripheral arteries. [2]
Atrial septostomy is a surgical procedure in which a small hole is created between the upper two chambers of the heart, the atria.This procedure is primarily used to palliate dextro-Transposition of the great arteries or d-TGA (often imprecisely called transposition of the great arteries), a life-threatening cyanotic congenital heart defect seen in infants.
Long-term follow-up studies now extend to more than 40 years post-operation [4] and there are numerous patients thriving in their 50s. A Facebook group, Mustard or Senning Survivors, [ 5 ] gathers several hundred global survivors in their 20s to 50s into a single community, supporting adults born with TGA that have had a Mustard, Senning ...
The calibrated automated thrombogram (CAT or CT) is a thrombin generation assay (TGA) and global coagulation assay (GCA) which can be used as a coagulation test to assess thrombotic risk. [1] [2] It is the most widely used TGA. [3] The CAT is a semi-automated test performed in a 96-well plate and requires specialized technologists to be ...
At that time, the procedure was used for patients who had TGA with a ventricular septal defect (VSD). By the late 2000s, the procedure was employed in situations where the right ventricle is bigger than the left ventricle and the left ventricle connects to the pulmonary artery instead of the aorta ; examples include double inlet left ventricle ...