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  2. Hydroxyproline - Wikipedia

    en.wikipedia.org/wiki/Hydroxyproline

    Hydroxyproline is a major component of the protein collagen, [3] comprising roughly 13.5% of mammalian collagen. Hydroxyproline and proline play key roles for collagen stability. [ 4 ] They permit the sharp twisting of the collagen helix. [ 5 ]

  3. Procollagen-proline dioxygenase - Wikipedia

    en.wikipedia.org/wiki/Procollagen-proline_di...

    Procollagen-proline dioxygenase catalyzes the following reaction: L-proline + alpha-ketoglutaric acid + O 2 → (2S, 4R)-4-hydroxyproline + succinate + CO 2. The mechanism for the reaction is similar to that of other dioxygenases, and occurs in two distinct stages: [3] In the first, a highly reactive Fe(IV)=O species is produced.

  4. Madin-Darby canine kidney cells - Wikipedia

    en.wikipedia.org/wiki/Madin-Darby_Canine_Kidney...

    Following the initial isolation in 1958 of epithelial cells from the kidney tubule of an adult Cocker Spaniel dog by Stewart H. Madin and Norman B. Darby, Jr., [3] the cell line bearing their name was employed primarily as a model for viral infection of mammalian cells.

  5. Collagen helix - Wikipedia

    en.wikipedia.org/wiki/Collagen_helix

    In 1954, Ramachandran & Kartha (13, 14) advanced a structure for the collagen triple helix on the basis of fiber diffraction data. It consists of a triple helix made of the repetitious amino acid sequence glycine-X-Y, where X and Y are frequently proline or hydroxyproline. [2] [3] Collagen folded into a triple helix is known as tropocollagen.

  6. Tanning (leather) - Wikipedia

    en.wikipedia.org/wiki/Tanning_(leather)

    Masking agents allow the tanner to further increase the pH to increase collagen's reactivity without inhibiting the penetration of the chromium(III) complexes. Collagen is characterized by a high content of glycine, proline, and hydroxyproline, usually in the repeat -gly-pro-hypro-gly-. [15] These residues give rise to collagen's helical structure.

  7. Scientists launch study to determine whether dogs can predict ...

    www.aol.com/scientists-launch-study-determine...

    Dogs are among the animals taking part in research to determine how much animals know about impending natural disasters

  8. Prolidase deficiency - Wikipedia

    en.wikipedia.org/wiki/Prolidase_deficiency

    Collagen is a structural protein found i.a. in bone, skin and connective tissues that is broken down into iminodipeptides at the end of its lifecycle. Of these dipeptides, those containing C-terminal proline or hydroxyproline would normally be broken down further by the enzyme Prolidase , recovering and thus recycling the constituent amino acids.

  9. Dietitians Say These Are the Best Intermittent Fasting Apps ...

    www.aol.com/dietitians-best-intermittent-fasting...

    “It helps me remember to drink more water, I do use their exercises sometimes, and of course the recipes. Haven’t had any issues with the app itself, always works. It has everything all in one ...