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A red blood cell in a hypotonic solution, causing water to move into the cell A red blood cell in a hypertonic solution, causing water to move out of the cell. Hemolysis or haemolysis (/ h iː ˈ m ɒ l ɪ s ɪ s /), [1] also known by several other names, is the rupturing of red blood cells (erythrocytes) and the release of their contents into surrounding fluid (e.g. blood plasma).
Symptoms of hemolytic anemia include those that can occur in all anemias as well as the specific consequences of hemolysis. All anemias can cause fatigue, shortness of breath, decreased ability to exercise when severe. Symptoms specifically related to hemolysis include jaundice and dark colored urine due to the presence of hemoglobin ...
(left) α-hemolysis (S. mitis); (middle) β-hemolysis (S. pyogenes); (right) γ-hemolysis (non-hemolytic, S. salivarius) Hemolysis is the breakdown of red blood cells. The ability of bacterial colonies to induce hemolysis when grown on blood agar is used to classify certain microorganisms. This is particularly useful in classifying ...
Hemolysis (the rupture of red blood cells) due to acute poisoning can cause anemia and hemoglobin in the urine. [42] Damage to kidneys can cause changes in urination such as acquired Fanconi syndrome and decreased urine output. [42] People who survive acute poisoning often go on to display symptoms of chronic poisoning. [42]
Autoimmune hemolysis might be a precursor of later onset systemic lupus erythematosus. [5] The terminology used in this disease is somewhat ambiguous. Although MeSH uses the term "autoimmune hemolytic anemia", [6] some sources prefer the term "immunohemolytic anemia" so drug reactions can be included in this category.
Hemolysis secondary to drug toxicity [15] Thalassemia minor [16] Congenital dyserythropoietic anemia [17] The above list is not exhaustive, and rare causes of hemolysis such as Bartonella infection, [18] hemolysis due to transfusion reactions, [19] and microangiopathic hemolytic anemia [20] should be suspected when symptoms specific to those ...
Red blood cell aggregates are counted as single cells by the automated analyzers used to run complete blood count tests. This leads to a markedly decreased red blood cell count and hematocrit and markedly elevated mean cell volume and mean cell hemoglobin concentration.
Disseminated intravascular hemolysis [2] Thrombotic thrombocytopenic purpura [2] Typical and atypical hemolytic uremic syndrome [2] Other microvascular abnormalities; Hypersplenism [2] Hemolytic anemia due to toxic effects on the membrane Spur cell anemia; External toxins Animal or spider bites [2] Metals; Organic compounds [2] Infectious agents