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Stabilizing selection (not to be confused with negative or purifying selection [1] [2]) is a type of natural selection in which the population mean stabilizes on a particular non-extreme trait value. This is thought to be the most common mechanism of action for natural selection because most traits do not appear to change drastically over time ...
In natural selection, negative selection [1] or purifying selection is the selective removal of alleles that are deleterious. This can result in stabilising selection through the purging of deleterious genetic polymorphisms that arise through random mutations.
The K a /K s ratio is used to infer the direction and magnitude of natural selection acting on protein coding genes. A ratio greater than 1 implies positive or Darwinian selection (driving change); less than 1 implies purifying or stabilizing selection (acting against change); and a ratio of exactly 1 indicates neutral (i.e. no) selection.
Middle (Graph 2) represents stabilizing selection with the moderate trait favored. Bottom (Graph 3) represents disruptive selection with both extremes being favored. In population genetics , directional selection is a type of natural selection in which one extreme phenotype is favored over both the other extreme and moderate phenotypes.
Biological constraints are factors which make populations resistant to evolutionary change. One proposed definition of constraint is "A property of a trait that, although possibly adaptive in the environment in which it originally evolved, acts to place limits on the production of new phenotypic variants."
The first and most common function to estimate fitness of a trait is linear ω =α +βz, which represents directional selection. [1] [10] The slope of the linear regression line (β) is the selection gradient, ω is the fitness of a trait value z, and α is the y-intercept of the fitness function.
A study of recent polygenic adaptation in the English has shown that selection on height has had small effects on allele frequencies (<1%) across most of the genome, and found evidence for polygenic adaptation in a wide variety of other traits as well including selection for increased infant birth size and increased female hip and waist size. [10]
Genetic drift is the process by which allele frequencies fluctuate within populations. Natural selection and genetic drift propel evolution forward, and through evolution, alleles can become fixed. [8] [9] Processes of natural selection such as sexual, convergent, divergent, or stabilizing selection pave the way for allele fixation. One way ...