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Tazarotene is most commonly used topically to treat acne vulgaris and psoriasis. [4] Like other topical retinoids, such as tretinoin and adapalene, tazarotene can be combined with benzoyl peroxide or an oral antibiotic, such as clindamycin or dapsone, for the treatment of acne. [8] This results in increased efficacy compared to tazarotene ...
Unlike the retinoid tretinoin (Retin-A), adapalene has also been shown to retain its efficacy when applied at the same time as benzoyl peroxide due to its more stable chemical structure. [19] Furthermore, photodegradation of the molecule is less of a concern in comparison to tretinoin and tazarotene. [7]
Third generation retinoids have narrow biological roles due to their constrained structure, with adapalene mimicking the effects of isotretinoin, [10] bexarotene binding only the Retinoid X receptors, and tazarotene binding the Retinoic acid receptor beta and Retinoic acid receptor gamma forms. [11]
Prescription retinoids: Prescription retinoids like tretinoin and tazarotene are already in the retinoic acid form, making them the strongest and most potent—meaning they also carry a higher ...
Adapalene Gel 0.1% Acne Treatment Differin, an over-the-counter acne gel cream that was previously available only with a prescription, is arguably the most one-size-fits-all acne treatment around.
Tretinoin, also known as all-trans retinoic acid (ATRA), is a medication used for the treatment of acne and acute promyelocytic leukemia. [ 8 ] [ 9 ] [ 10 ] For acne, it is applied to the skin as a cream, gel or ointment. [ 10 ]
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