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Metformin can also impair the absorption of calcium and vitamin B12 from your gut, Dr. Gupta adds, “so it is important to take additional vitamin B12 supplementation and maintain adequate ...
Metformin can also cause a vitamin B12 deficiency, which may be linked with anemia. Stopping the medication or starting vitamin B12 supplementation appears to reverse this. Seek medical advice if ...
It is believed that malabsorption of vitamin B 12 in diabetic patients, is due to individuals taking metformin therapy (an insulin sensitizer used for treating type 2 diabetes). [81] Furthermore, obese individuals with type 2 diabetes are likely to develop gastroesophageal reflux disease, [ 82 ] and take proton pump inhibitors, which further ...
Left untreated, vitamin B12 deficiencies can lead to serious health problems including neurological problems and anemia. [88] Although more research is needed to understand the mechanisms of this association, it is suggested that people who take metformin monitor their vitamin B12 levels and if low, begin supplementation. [87]
Metformin and Vitamin B12 Vitamin B12 deficiency is associated with a number of problems, including weakness, weight loss, constipation and — yes — hair loss.
Reduced serum levels of vitamin B 12 occur in up to 30% of people taking long-term anti-diabetic metformin. [ 102 ] [ 103 ] Deficiency does not develop if dietary intake of vitamin B 12 is adequate or prophylactic B 12 supplementation is given.