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Naples Plague: Bubonic plague 1.25 million – 1656–1658 Southern Italy 17 1889–1890 pandemic: Influenza or human coronavirus OC43 [16] [17] 1 million – 1889–1890 Worldwide 18 1629–1631 Italian plague: Bubonic plague 1 million – 1629–1631 Italy 19 1846–1860 cholera pandemic: Cholera: 1 million – 1846–1860 Worldwide
The 1918 influenza pandemic has been declared, according to Barry's text, as the 'deadliest plague in history'. The extensiveness of this declaration can be supported through the following statements: "the greatest medical holocaust in history" [2] and "the pandemic ranks with the plague of Justinian and the Black Death as one of the three most destructive human epidemics". [3]
In the first half of the 17th century, the Great Plague of Milan claimed some 1.7 million victims in Italy, or about 14% of the population. [47] In 1656, the plague killed about half of Naples' 300,000 inhabitants. [48] More than 1.25 million deaths resulted from the extreme incidence of plague in 17th-century Spain. [49]
From the 14th century bubonic plague to the more recent emergence of AIDS in the 1980's, Laci breaks down the top 5 deadliest pandemics in human history. Related Gallery: Ebola in 2014.
The Spanish Flu, the second deadliest pandemic in history after the bubonic plague, along with the aftermath of World War I and ensuing political and social chaos, made 1918 a tough time to be alive.
Plague, one of the deadliest bacterial infections in human history, caused an estimated 50 million deaths in Europe during the Middle Ages when it was known as the Black Death.
However, John Barry stated in his 2004 book The Great Influenza: The Epic Story of the Deadliest Plague In History that researchers have found no evidence to support this position. [83] Another theory holds that the 1918 virus mutated extremely rapidly to a less lethal strain.
One of the worst plagues in history, the Black Death arrived on the shores of Europe in 1347. Five years later, around 25 to 50 million people were dead across the continent.