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Magnesium sulfate is effective in decreasing the risk that pre-eclampsia progresses to eclampsia. [24] Intravenous magnesium sulfate is used to prevent and treat seizures of eclampsia. It reduces the systolic blood pressure but does not alter the diastolic blood pressure, so the blood perfusion to the fetus is not compromised.
In general, the treatment of postpartum preeclampsia is the same as during pregnancy, including using anti-hypertensive medications to lower blood pressure and magnesium sulfate to prevent eclampsia. The same blood pressure medications that are used during pregnancy can be used in the postpartum period.
The use of intravenous or intramuscular magnesium sulfate improves outcomes in those with severe pre-eclampsia and eclampsia and is generally safe. [ 4 ] [ 13 ] Treatment options include blood pressure medications such as hydralazine and emergency delivery of the baby either vaginally or by cesarean section .
Magnesium sulfate [40] Myosin light chain inhibitor Probably effective in delaying preterm birth by 48 hours. [8] It is used for its neuro-protective effects since it is shown to decrease the risk of cerebral palsy in infants. [41] Absolute contraindication: myasthenia gravis. [42] Use as a tocolytic agent may result in death of the fetus or ...
As a bronchodilator after beta-agonist and anticholinergic agents have been tried, e.g. in severe exacerbations of asthma. [4]Obstetrics: Magnesium sulfate is used to prevent seizures in women with preeclampsia and eclampsia, and is also used for fetal neuroprotection in preterm deliveries, but has been shown to be an ineffective tocolytic agent.
In women with preeclampsia or eclampsia, magnesium sulfate is often prescribed to prevent the occurrence of seizures in the gestational parent. [13] Treatment should be continued from the time of diagnosis to several weeks postpartum given the increased risk of medical complications immediately following delivery of the fetus. [ 24 ]
Magnesium sulfate or magnesium sulphate is a chemical compound, a salt with the formula MgSO 4, consisting of magnesium cations Mg 2+ (20.19% by mass) and sulfate anions SO 2− 4. It is a white crystalline solid , soluble in water but not in ethanol .
If maternal preeclampsia [34] is the underlying cause of fetal growth restriction (FGR) antihypertensive therapy and magnesium sulfate are potential therapies. [12] Antihypertensive treatment is used to reduce blood pressure and prevent pulmonary edema and cerebral hemorrhages.
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