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Metformin can also impair the absorption of calcium and vitamin B12 from your gut, Dr. Gupta adds, “so it is important to take additional vitamin B12 supplementation and maintain adequate ...
It is believed that malabsorption of vitamin B 12 in diabetic patients, is due to individuals taking metformin therapy (an insulin sensitizer used for treating type 2 diabetes). [81] Furthermore, obese individuals with type 2 diabetes are likely to develop gastroesophageal reflux disease, [ 82 ] and take proton pump inhibitors, which further ...
Reduced serum levels of vitamin B 12 occur in up to 30% of people taking long-term anti-diabetic metformin. [ 102 ] [ 103 ] Deficiency does not develop if dietary intake of vitamin B 12 is adequate or prophylactic B 12 supplementation is given.
But Cohen says there are plenty of other risk factors for vitamin B12 deficiency, including taking the diabetes drug metformin and certain medications for gastroesophageal reflux disease (GERD ...
Left untreated, vitamin B12 deficiencies can lead to serious health problems including neurological problems and anemia. [88] Although more research is needed to understand the mechanisms of this association, it is suggested that people who take metformin monitor their vitamin B12 levels and if low, begin supplementation. [87]
“Vitamin B12 requirements are low because we can store up to 2,500 micrograms in the liver,” says Ryan D. Andrews, R.D., C.S.C.S., principal nutritionist at Precision Nutrition. So target just ...
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