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Angioleiomyoma (vascular leiomyoma, angiomyoma) of the skin is thought to arise from vascular smooth muscle, and is generally acquired. [3] Angioleiomyomas appear as small (<2 cm), firm, movable, slow growing subcutaneous nodules. Pain is a common symptom. They are most commonly seen on the extremities. The cause of angioleiomyoma is unknown.
No or mild atypia, no tumor cell necrosis ⇒ leiomyoma. If 5 or more mitotic figures are present in 10 high powered fields but the behavior still appears benign, may append “with significant mitotic activity”. Moderate to severe atypia without tumor cell necrosis atypical leiomyoma if < 10 mitotic figures per high power field or
Cutaneous leiomyoma, also known as leiomyoma cutis, [1] or cutaneous leiomyomata, [2] is a benign skin tumor made of smooth muscle cells. [3] There are three different types of cutaneous leiomyomas, genital leiomyomas, angioleiomyomas, and piloleiomyomas. Cutaneous leiomyomas can occur sporadically or as a part of a genetic condition.
Leiomyoma enucleated from a uterus. External surface on left; cut surface on right. Micrograph of a small, well-circumscribed colonic leiomyoma arising from the muscularis mucosae and showing fascicles of spindle cells with eosinophilic cytoplasm and elongated, cigar-shaped nuclei Immunohistochemistry for β-catenin in uterine leiomyoma, which is negative as there is only staining of cytoplasm ...
As the skin lesions are typically painful, it is also often necessary to exclude other painful tumors of the skin (including blue rubber bleb nevus, leiomyoma, eccrine spiradenoma, neuroma, dermatofibroma, angiolipoma, neurilemmoma, endometrioma, glomus tumor and granular cell tumor; the mnemonic "BLEND-AN
Intravenous Leiomyoma Intravenous leiomyomatosis is a rare condition seen exclusively in women in which leiomyomata , benign smooth muscle tumors, are found in veins . The masses are benign-appearing but can spread throughout the venous system leaving the uterus and even cause death when growing into the heart from the IVC. [ 1 ]
Benign lipoblastomatosis is a tumor consisting of fetal-embryonal adipocytes, frequently confused with a liposarcoma, affecting exclusively infants and young children, with approximately 90% of cases occurring before 3 years of age.
An enucleated uterine leiomyoma – external surface on left, cut surface on right Fibroids are a type of uterine leiomyoma . Fibroids grossly appear as round, well circumscribed (but not encapsulated), solid nodules that are white or tan, and show whorled appearance on histological section.