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A glomus tumor (also known as a "solitary glomus tumor" [1]) is a rare neoplasm arising from the glomus body and mainly found under the nail, on the fingertip or in the foot. [2]: 670 They account for less than 2% of all soft tissue tumors. [3] The majority of glomus tumors are benign, but they can also show malignant features. [4]
Studies conducted in the past have also revealed changes in the expression of Bcl-2 and p53 in comparison to benign glomus tumors. [ 3 ] [ 12 ] These lesions in soft tissue and skin need to be distinguished from other cutaneous round cell malignancies such hemangiopericytoma , leiomyosarcoma , melanoma , and Merkel cell carcinoma .
Cancer Treatment Centers of America (CTCA) was founded in 1988 by Richard J. Stephenson following the death of his mother, Mary Brown Stephenson, who died from lung cancer. [3] Stephenson purchased the American International Hospital in Zion, Illinois , in 1988 and expanded the hospital to include a radiation center, the Mary Brown Stephenson ...
Hildreth's sign is a physical examination technique useful in differentiating glomus tumors and hemangiopericytomas from other masses with a similar appearance. It was first described by DH Hildreth, in 1970. [1]
A glomectomy is an excision of a glomus body or a glomus cell, usually in the case of a glomus tumor. This operation was formerly performed for the treatment of severe, chronic asthma , [1] but has since been abandoned for this purpose due to its lack of efficacy.
Glomus tympanicum and Glomus jugulare, also known as jugulotympanic paraganglioma: Both commonly present as a middle ear mass resulting in tinnitus (in 80%) and hearing loss (in 60%). The cranial nerves of the jugular foramen may be compressed, resulting swallowing difficulty, or ipsilateral weakness of the upper trapezius and ...
Glomus tumor Dermatofibroma Infantile myofibromatosis: Neurofilament: Neurofibroma: Neuro-specific enolase: Merkel cell carcinoma: Non-aqueous alcoholic eosin stain (NAES) Pseudogout: Oil red O: Sebaceous carcinoma Angiokeratoma corporis diffusum Subcutaneous fat necrosis of the newborn: Peanut agglutinin: Basal cell carcinoma: Phosphotungsten ...
Treatment options for soft-tissue sarcomas include surgery, radiotherapy, chemotherapy, and targeted drug therapy. [3] Surgery is the most common treatment for soft-tissue sarcomas, and usually the only way to achieve a cure. The tumor is removed leaving a safe margin of surrounding healthy tissue to decrease the chances of its recurrence.