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Carotid bodies are considered the primary peripheral chemoreceptor and have been shown to contribute more to a hypoxic response. However, in the chronic absence of the carotid body, the aortic body is able to perform a similar respiratory regulatory role, suggesting that it possesses efficacious mechanisms of signal transduction as well. [5]
The aortic bodies are collections of chemoreceptors present on the aortic arch. [1] Most are located above the aortic arch, [2] while some are located on the posterior side of the aortic arch between it and the pulmonary artery below. [3] They consist of glomus cells and sustentacular cells. [1] Some sources equate the "aortic bodies" and ...
The carotid body is a small cluster of peripheral chemoreceptor cells and supporting sustentacular cells situated at the bifurcation of each common carotid artery in its tunica externa. [ 1 ] [ 2 ] The carotid body detects changes in the composition of arterial blood flowing through it, mainly the partial pressure of arterial oxygen , but also ...
The carotid body is not labelled but is located within the wall of the internal carotid artery near the bifurcation of the common carotid artery. Glomus type I cells are the chemoreceptor cells found in the carotid body. Glomus cells are the cell type mainly located in the carotid bodies and aortic bodies. Glomus type I cells are peripheral ...
change of blood pH, detected by peripheral chemoreceptors in the aortic bodies and in the carotid bodies. [4] change of blood pressure, detected by arterial baroreceptors in the aortic arch and the carotid sinuses. [2] various other inputs from the hypothalamus, thalamus, and cerebral cortex. [4]
Peripheral chemoreceptors (carotid and aortic bodies) and central chemoreceptors (medullary neurons) primarily function to regulate respiratory activity. This is an important mechanism for maintaining arterial blood pO2, pCO2 , and pH within appropriate physiological ranges.
Arterial baroreceptors are located in the carotid sinus (at the bifurcation of common carotid artery into external and internal carotids) and in the aortic arch. [5] The baroreceptors can identify the changes in both the average blood pressure or the rate of change in pressure with each arterial pulse.
The aortic nerve is an autonomic afferent nerve, [1] and runs from the peripheral baroreceptors and chemoreceptors found in the aortic arch and the bifurcation of the right brachiocephalic trunk. [2] [3] It joins the vagus nerve. [2] [3] This allows for impulses to reach the solitary tract of the brainstem. [2]
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