Search results
Results from the WOW.Com Content Network
Phenylpropanolamine (PPA), sold under many brand names, is a sympathomimetic agent used as a decongestant and appetite suppressant. [9] [1] [10] [11] It was once common in prescription and over-the-counter cough and cold preparations.
Flunarizine is a selective calcium antagonist with moderate other actions including antihistamine, serotonin receptor blocking and dopamine D 2 blocking activity. Compared to other calcium channel blockers such as dihydropyridine derivatives, verapamil and diltiazem, flunarizine has low affinity to voltage-dependent calcium channels.
Bucinnazine (AP-237, 1-butyryl-4-cinnamylpiperazine) is an opioid analgesic drug that was widely used in China to treat pain in cancer patients as of 1986. [1] It is one of the most potent compounds among a series of piperazine- amides first synthesized and reported in Japan in the 1970s.
Clemastine, also known as meclastin, is a first-generation H1 histamine antagonist (antihistamine) with anticholinergic properties (drying) and sedative side effects. [1] Like all first-generation antihistamines, it is sedating. [2] [3] Patented in 1960, it came into medical use in 1967. [4]
Halogenation of the alcohol in muriatic acid afforded 4-Chlorobenzhydryl chloride [134-83-8] (3). Alkylation with one equivalent of piperazine gives 1-(4-Chlorobenzhydryl)piperazine [303-26-4] ( 4 ). Alkylation of the remaining nitrogen with Cinnamyl Bromide [4392-24-9] ( 5 ) completed the synthesis of Clocinizine ( 6 ).
Once ingested, the substance is absorbed quite rapidly and reaches a peak plasma concentration in 1–3 hours post-administration. [28] [2] [29] Cmax, the maximum level of the drug in the tested area (typically blood plasma), has been measured to be 275 ± 36 ng/mL; t max, the time to maximum concentration, was 3.0 ± 0.5 hours. [2]
Benzyl (2E)-3-phenylprop-2-enoate. Other names Benzyl cinnamate Cinnamein Benzyl cinnamoate ... 238.286 g·mol −1 Appearance White to pale yellow solid [1]
Ambroxol is available as syrup, tablets, pastilles, dry powder sachets, inhalation solution, drops and ampules as well as effervescent tablets. Ambroxol also provides pain relief in acute sore throat. Pain in sore throat is the hallmark of acute pharyngitis. [3] Sore throat is usually caused by a viral infection. The infection is self limited ...