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Lugol's iodine is a liquid made up of two parts potassium iodide for every one part elemental iodine in water. [8] Lugol's iodine was first made in 1829 by the French physician Jean Lugol. [7] [8] It is on the World Health Organization's List of Essential Medicines. [9] [10] Lugol's iodine is available as a generic medication and over the ...
Nevertheless, the iodide in tincture of iodine used as a water disinfectant does supply more than adequate nutritional iodine, perhaps 30 or more times the recommended daily allowance per liter or quart. Application of tincture or Lugol's to the skin also results in absorption and bioavailability of some moderate fraction of the iodine.
Tincture of iodine: iodine in ethanol, or iodine and sodium iodide in a mixture of ethanol and water. Lugol's iodine: iodine and iodide in water alone, forming mostly triiodide. Unlike tincture of iodine, Lugol's iodine has a minimised amount of the free iodine (I 2) component. Iodine glycerin, a preparation used in dentistry.
These dosages list mass of potassium iodide rather than elemental iodine. [17] [16] Potassium iodide can be administered as tablets or as Lugol's iodine solution. [16] The same dosage is recommended by the US Food and Drug Administration. [18] A single daily dose is typically sufficient for 24-hour protection. [16]
Wrong timing of iodine use may even increase the risk by triggering the Plummer effect. [10] The Plummer effect is, however, helpful in the management of thyrotoxicosis, where the usage of Lugol’s solution helps to limit the release of thyroid hormones into the bloodstream. [4]
This allows Lugol's iodine to be produced in strengths varying from 2% to 15% iodine. Elemental iodine (I 2) is poisonous if taken orally in large amounts; 2–3 grams is a lethal dose for an adult human. [71] [72] Iodine vapor is very irritating to the eye, to mucous membranes, and in the respiratory tract.
Gram noticed that some bacterial cells possessed noticeable resistance to decolorization. Based on these observations, Gram developed the initial gram staining procedure, initially making use of Ehrlich's aniline-gentian violet, Lugol's iodine, absolute alcohol for decolorization, and Bismarck brown for counterstain. [6]
Povidone-iodine is a chemical complex of povidone, hydrogen iodide, and elemental iodine. [4] The recommended strength solution contains 10% Povidone, with total iodine species equaling 10,000 ppm or 1% total titratable iodine. [4] It works by releasing iodine which results in the death of a range of microorganisms. [1]
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