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The spinothalamic tract is a nerve tract in the anterolateral system in the spinal cord. [1] This tract is an ascending sensory pathway to the thalamus . From the ventral posterolateral nucleus in the thalamus, sensory information is relayed upward to the somatosensory cortex of the postcentral gyrus .
The spinohypothalamic tract or spinohypothalamic fibers is a sensory fiber tract projecting from the spinal cord to the hypothalamus directly to mediate reflex autonomic and endocrine responses to painful stimuli (the hypothalamus receives additional indirect nociceptive projections from the reticular formation (see: spinoreticular tract), and periaqueductal gray (see: spinomesencephalic tract).
The ventral posterior nucleus receives neuronal input from the medial lemniscus, spinothalamic tracts, and trigeminothalamic tract. It projects to the somatosensory cortex and the ascending reticuloactivation system.
The spinothalamic tract is normally divided at the level C1-C2. Open cordotomy, which requires a laminectomy (removal of part of one or more vertebrae), takes place under general anaesthetic and has a longer recovery time and a higher risk of side-effects including permanent weakness. However, it is still sometimes used where percutaneous ...
The spinomesencephalic pathway, spinomesencephalic tract or spino-quadrigeminal system of Mott, includes a number of ascending tracts in the spinal cord, including the spinotectal tract. [1] [2] [3] The spinomesencephalic tract is one of the ascending tracts in the anterolateral system of the spinal cord that projects to various parts of the ...
The marginal nucleus of spinal cord, posteromarginal nucleus, or spinal lamina 1 (Rexed lamina 1) is located at the most dorsal aspect of the posterior grey column of the spinal cord. The neurons located here receive input primarily from Lissauer's tract and relay information related to pain and temperature sensation.
The ascending pain and temperature fibers of the spinothalamic tract send information to the PAG via the spinomesencephalic pathway (so-named because the fibers originate in the spine and terminate in the PAG, in the mesencephalon or midbrain). This region has been used as the target for brain-stimulating implants in patients with chronic pain.
The tract descends through the periaqueductal gray, [5] through the dorsal longitudinal fasciculus, [1] and adjacent to the reticular formation. [5] In the brainstem, it descends in the lateral tegmentum of the midbrain, pons, and medulla oblongata. In the spinal cord, it descends in the dorsolateral quadrant of the lateral funiculus. [6]