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Ephedrine promotes modest short-term weight loss, [24] specifically fat loss, but its long-term effects are unknown. [25] In mice, ephedrine is known to stimulate thermogenesis in the brown adipose tissue, but because adult humans have only small amounts of brown fat, thermogenesis is assumed to take place mostly in the skeletal muscle.
Guaifenesin is used in combination with, for example, ketamine, since guaifenesin does not provide analgesia or produce unconsciousness. [26] [27] In horses, the drug's biological half-life is 77 minutes. Premedication with xylazine (1.1 mg/kg) can reduce the dose required from 163 mg/kg (in geldings) to just 88 mg/kg. [27]
Bottle of ephedrine, an alkaloid found in ephedra. Ephedra is a medicinal preparation from the plant Ephedra sinica. [1] [a] Several additional species belonging to the genus Ephedra have traditionally been used for a variety of medicinal purposes, and are a possible candidate for the soma plant of Indo-Iranian religion. [3]
The tables below contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses.
Examples are ephedrine, phenylephrine, pseudoephedrine, and oxymetazoline. Fever or pain medication. Examples are paracetamol (acetaminophen) and NSAIDs such as ibuprofen or naproxen. Also employed are various substances supposed to soften the coughing, like honey or supplement syrup. An example combination is guaifenesin with codeine.
Guaifenesin/codeine is a fixed-dose combination cold medicine used for the treatment of cough. [1] It contains guaifenesin, an expectorant; and codeine, as the phosphate, an opioid antitussive. [1] It is taken by mouth. [1] It was approved for medical use in the United States in 2006. [1]
Conversely, ephedrine is the enantiopure (1R,2S)-enantiomer. [1] Racephedrine has been marketed for medical use in Italy . [ 1 ] Like ephedrine, racephedrine is a releasing agent of norepinephrine and to a much lesser extent of dopamine .
An estimated 75% of the efficacy of the ECA stack can be attributed to decreased appetite, while the remaining 25% is due to the thermogenic effects of the stack. [12] The stimulating effects of caffeine and ephedrine are an additional contributing factor to weight loss.
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