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Well, there’s no magic time, but you should take metformin at the same time each day and with food to avoid gastrointestinal side effects. If you’re taking extended-release metformin tablets ...
The most common side effects are gastrointestinal (everyone’s favs: diarrhea, bloating, stomach pain, gas, indigestion and constipation). These affect up to 30 percent of metformin users.
Metformin is a pleiotropic drug, with extensive off-target activity beyond its antidiabetic effect. Much of this has been attributed to its action on AMPK, although other mechanisms have been proposed. [221] [222] Metformin has been studied for its effects on multiple other conditions, including: Non-alcoholic fatty liver disease [223] [224] [225]
Although uncommon in the general population, ischemic colitis occurs with greater frequency in the elderly, and is the most common form of bowel ischemia. [1] [2] [3] Causes of the reduced blood flow can include changes in the systemic circulation (e.g. low blood pressure) or local factors such as constriction of blood vessels or a blood clot ...
Endoclips have found a primary application in hemostasis (or the stopping of bleeding) during endoscopy of the upper (through gastroscopy) or lower (through colonoscopy) gastrointestinal tract. [1] Many bleeding lesions have been successfully clipped, including bleeding peptic ulcers , [ 4 ] Mallory-Weiss tears of the esophagus , [ 8 ...
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Routine use of colonoscopy screening varies globally. In the US, colonoscopy is a commonly recommended and widely utilized screening method for colorectal cancer, often beginning at age 45 or 50, depending on risk factors and guidelines from organizations like the American Cancer Society. [9] However, screening practices differ worldwide.
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