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Selman Abraham Waksman (July 22, 1888 – August 16, 1973) was a Jewish American inventor, Nobel Prize laureate, biochemist and microbiologist whose research into the decomposition of organisms that live in soil enabled the discovery of streptomycin and several other antibiotics.
Streptomycin is an antibiotic medication used to treat a number of bacterial infections, [3] including tuberculosis, Mycobacterium avium complex, endocarditis, brucellosis, Burkholderia infection, plague, tularemia, and rat bite fever. [3] For active tuberculosis it is often given together with isoniazid, rifampicin, and pyrazinamide. [4]
[5] [6] Bugie was told that it was not important for her name to be on the patent as she would "one day get married and have a family". [1] [7] Waksman went on to win the Nobel Prize for Medicine in 1952 and took all the credit for the discovery of streptomycin. [1] Waksman claimed that Bugie was more involved in the discovery than Schatz. [8]
In the afternoon of 19 October, Schatz noticed that the tuberculosis bacteria were killed by his actinomycete extract, which he gave the name "streptomycin" [6] following the scientific name of the source and the earlier antibiotic streptothricin discovered by Waksman and H. Boyd Woodruff in 1942. [15]
The name was changed in 1948 by Waksman and Henrici to Streptomyces griseus. The interest in these strains stems from their ability to produce streptomycin, a compound which demonstrated significant bactericidal activity against organisms such as Yersinia pestis (the causative agent of plague) and Mycobacterium tuberculosis (the causative agent ...
1944 – streptomycin, the first aminoglycoside [2] 1947 – sulfadiazine; 1948 – chlortetracycline, the first tetracycline; 1949 – chloramphenicol, the first amphenicol [2] 1949 – neomycin; 1950 – oxytetracycline; 1950 – penicillin G procaine; 1952 – erythromycin, the first macrolide [2] 1954 – benzathine penicillin; 1955 ...
An amateur fossil hunter has uncovered a piece of animal vomit which dates back 66 million years on a beach in Denmark.
Streptomycin, discovered during a Merck-funded research program in Selman Waksman's laboratory at Rutgers in 1943, became the first effective treatment for tuberculosis. At the time of its discovery, sanitoriums for the isolation of tuberculosis-infected people were a ubiquitous feature of cities in developed countries, with 50% dying within 5 ...