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Tributyl phosphate, known commonly as TBP, is an organophosphorus compound with the chemical formula (CH 3 CH 2 CH 2 CH 2 O) 3 PO. This colourless, odorless liquid finds some applications as an extractant and a plasticizer .
Tributylphosphine is the organophosphorus compound with the chemical formula P(CH 2 CH 2 CH 2 CH 3) 3, often abbreviated as PBu 3.It is a tertiary phosphine.It is an oily liquid at room temperature, with a nauseating odor.
TBP is involved in DNA melting (double strand separation) by bending the DNA by 80° (the AT-rich sequence to which it binds facilitates easy melting). The TBP is an unusual protein in that it binds the minor groove using a β sheet. Another distinctive feature of TBP is a long string of glutamines in the N-terminus of the protein.
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TbP can be obtained by the reaction of terbium and red phosphorus at 800–1000 °C: 4 Tb + P 4 → 4 TbP. The compound can also be obtained by the reaction of sodium phosphide and anhydrous terbium chloride at 700~800 °C. [3]
Adam Dahlberg (born January 17, 1993), known online as SkyDoesMinecraft, Sky Does Everything and NetNobody, is an American YouTuber mainly known for formerly producing family-friendly content related to Minecraft.
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The degree of DNA bending is species and sequence dependent. For example, one study used the adenovirus TATA promoter sequence (5'-CGCTATAAAAGGGC-3') as a model binding sequence and found that human TBP binding to the TATA box induced a 97° bend toward the major groove while the yeast TBP protein only induced an 82° bend. [21]