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Primary central nervous system vasculitis Headache, cognitive impairment, stroke, encephalopathy, and seizures. [28] Retinal vasculitis: Visual impairments, floaters, and macular edema. [29] Secondary vasculitis [8] Lupus vasculitis: Palpable purpura, petechiae, papulonodular lesions, urticaria lesions, and mononeuritis multiplex. [30 ...
Differential diagnosis includes vascular malformation, angioma, pyogenic granuloma, angiosarcoma, epithelioid hemangioendothelioma, Kaposi’s sarcoma, and other more rare vascular tumors. Three forms of intravascular papillary endothelial hyperplasia exist: the primary or pure form, the secondary or mixed form, and the extravascular form.
Rheumatoid vasculitis may affect almost any organ in the body. The skin and peripheral nerves are the most frequently affected areas. Although major organ system involvement of the kidney, bowel, or heart is much less common, it can result in serious morbidity and mortality, such as renal failure, bowel ischemia, and myocardial infarction. [3]
Recurrent urticaria, with skin eruptions primarily affecting the trunk, face, and upper extremities, is the primary clinical manifestation of hypocomplementemic urticarial vasculitis (HUV). [31] Oral aphthae are the defining feature of Behçet's disease and manifest in 98% of patients. Compared to oral lesions, genital aphthae are less common. [3]
Cutaneous small-vessel vasculitis (CSVV) is inflammation of small blood vessels, usually accompanied by small lumps beneath the skin. [1]: 831 [2] The condition is also known as hypersensitivity vasculitis, cutaneous leukocytoclastic vasculitis, hypersensitivity angiitis, cutaneous leukocytoclastic angiitis, cutaneous necrotizing vasculitis and cutaneous necrotizing venulitis, [3]
High resolution MRI may show hyperenhancement of the blood vessel walls in primary CNS vasculitis and may help to distinguish the lesions form atherosclerotic plaques or reversible cerebral vasoconstriction syndrome which have similar morphology on angiography. MRI usually also shows multiple infarcts, enhancement of the leptomeninges (the ...
Lesions reflect leakage of plasma components across vascular endothelium and excessive extracellular matrix production by smooth muscle cells, usually secondary to hypertension. [ 11 ] Hyaline arteriolosclerosis is a major morphologic characteristic of benign nephrosclerosis , in which the arteriolar narrowing causes diffuse impairment of renal ...
Cutaneous vasculitis is the most common type of vasulitis amongst those with systemic lupus erythematosus. [7] The clinical presentation is variable and can include superficial ulcerations, splinter hemorrhages, panniculitis, macules, erythema with necrosis or erythematous plaques, cutaneous infarction, livedo reticularis, bullous lesions of the extremities or urticaria lesions, papulonodular ...
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