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Achlorhydria and hypochlorhydria refer to states where the production of hydrochloric acid in gastric secretions of the stomach and other digestive organs is absent or low, respectively. [1] It is associated with various other medical problems.
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The Heidelberg test is a medical diagnostic test used in the diagnosis of hypochlorhydria, i.e. insufficient hydrochloric acid in the stomach, hyperchlorhydria, achlorhydria, and for suspected bile reflux. When performing the Heidelberg test, the patient swallows a small electronic device about the size of a vitamin capsule.
Hypochloremia (or Hypochloraemia) is an electrolyte disturbance in which there is an abnormally low level of the chloride ion in the blood.The normal serum range for chloride is 97 to 107 mEq/L. [citation needed]
Symptoms of hypernatremia may vary depending on type and how quickly the electrolyte disturbance developed. [27] Common symptoms are dehydration, nausea, vomiting, fatigue, weakness, increased thirst, and excess urination. Patients may be on medications that caused the imbalance such as diuretics or nonsteroidal anti-inflammatory drugs. [27]
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Sometimes, surgery may be needed to ease symptoms. [13] Chronic inflammation of the gastric mucosa can lead to atrophic gastritis resulting in a decreased secretion of gastric acid, and consequent digestive problems. In hypochlorhydria and achlorhydria, gastric acid is either low or absent, respectively
Ménétrier disease is a rare, acquired, premalignant disease of the stomach characterized by massive gastric folds, gastric hyperplasia, excessive mucus production with resultant protein loss, and little or no acid production (achlorhydria).