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Antifungal resistance is a One Health concern, driven by multiple extrinsic factors, including extensive fungicidal use, overuse of clinical antifungals, environmental change and host factors. [ 1 ] Like resistance to antibacterials, antifungal resistance can be driven by antifungal use in agriculture.
Most antifungal drugs induce fungal cell death by destroying the cell wall of the fungus. These drugs inhibit the production of ergosterol, which is a fundamental component of the fungal cell membrane and wall. Antifungal drugs are generally classified according to their chemical structures and their corresponding mechanism of actions.
Antifungal medication, used to treat or prevent fungal infections Fungicide , an anti-fungal substance that kills fungi Fungistatics , anti-fungal substances that prevent fungi from growing or reproducing
Treatment is generally performed using antifungal medicines, usually in the form of a cream or by mouth or injection, depending on the specific infection and its extent. [15] Some require surgically cutting out infected tissue. [3] Fungal infections have a world-wide distribution and are common, affecting more than one billion people every year ...
Antimicrobial use has been common practice for at least 2000 years. Ancient Egyptians and ancient Greeks used specific molds and plant extracts to treat infection. [5]In the 19th century, microbiologists such as Louis Pasteur and Jules Francois Joubert observed antagonism between some bacteria and discussed the merits of controlling these interactions in medicine. [6]
Primary nursing is a system of nursing care delivery that emphasizes continuity of care and responsibility acceptance by having one registered nurse (RN), often teamed with a licensed practical nurse (LPN) and/or nursing assistant (NA), who together provide complete care for a group of patients throughout their stay in a hospital unit or department. [1]
Fluconazole is a fungistatic antifungal medication that is administered orally or intravenously. It is used to treat a variety of fungal infections, especially Candida infections of the vagina ("yeast infections'), mouth, throat, and bloodstream.
Barrier nursing is a set of stringent infection control techniques used in nursing. The aim of barrier nursing is to protect medical staff against infection by patients and also protect patients with highly infectious diseases from spreading their pathogens to other non-infected people. Barrier nursing was created as a means to maximize ...