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2. Dimethyl fumarate - Wikipedia

   en.wikipedia.org/wiki/Dimethyl_fumarate

   The Swiss company Fumapharm eventually brought Fumaderm, an oral formulation of dimethyl fumarate (along with some monoesters) to market for psoriasis in Germany in 1994. [ 16 ] [ 17 ] [ 18 ] Based on the efficacy and safety of this formulation, and evidence that dimethyl fumarate was the main active component, an oral formulation of dimethyl ...

3. Biogen - Wikipedia

   en.wikipedia.org/wiki/Biogen

   In May 2006, the company announced it would acquire cancer specialist, Conforma Therapeutics for $250 million. [12] Later in the same month, the company announced its intention to acquire Fumapharm AG, consolidating ownership of Fumaderm and BG-12, an oral fumarate, which was being studied for the treatment of multiple sclerosis and psoriasis. [13]

4. TNF inhibitor - Wikipedia

   en.wikipedia.org/wiki/TNF_inhibitor

   A TNF inhibitor is a pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the inflammatory response.TNF is involved in autoimmune and immune-mediated disorders such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, psoriasis, hidradenitis suppurativa and refractory asthma, so TNF inhibitors may be used in their ...

5. Fumaderm - Wikipedia

   en.wikipedia.org/?title=Fumaderm&redirect=no

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6. Risankizumab - Wikipedia

   en.wikipedia.org/wiki/Risankizumab

   Risankizumab was approved by the U.S. Food and Drug Administration (FDA) for treatment of moderate-to-severe plaque psoriasis in April 2019. [13] [10] [14]The FDA approved risankizumab based on evidence primarily from five clinical trials (Trial 1/NCT02684370, Trial 2/NCT02684357, Trial 3/NCT02672852, Trial 4/ NCT02694523, and Trial 5/NCT02054481) of 1606 participants with moderate to severe ...

7. Etanercept - Wikipedia

   en.wikipedia.org/wiki/Etanercept

   It has US Food and Drug Administration (FDA) approval to treat rheumatoid arthritis, juvenile idiopathic arthritis and psoriatic arthritis, plaque psoriasis and ankylosing spondylitis. Tumor necrosis factor alpha (TNFα) is the "master regulator" of the inflammatory (immune) response in many organ systems. Autoimmune diseases are caused by an ...